The Registry of Toxic Effects of Chemical Substances

Benzoic acid, butyl ester

RTECS #: DG4925000

CAS #: 136-60-7

UPDATE: June 1998 MW: 178.25 MF: C11H14O2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. Anthrapole AZ
  2. Benzoic acid n - butyl ester
  3. Butyl benzoate
  1. Butylester kyseliny benzoove (Czech)
  2. Dai Cari XBN
  3. n - Butyl benzoate


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
skin
rabbit 		500 mg open irritation test moderate UCDS** 10/15/1958


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
mouse 		lethal dose (50 percent kill): 3,450 mg/kg Behavioral: Convulsions or effect on seizure threshold

Gastrointestinal: Other changes

Blood: Hemorrhage 		NTIS** OTS0539230
oral
rat 		lethal dose (50 percent kill): 735 mg/kg N/R NPIRI* 2,7,1975
skin
rabbit 		lethal dose (50 percent kill): 4 gm/kg N/R NPIRI* 2,7,1975


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 80635;
Number of Industries 4;
Total Number of Facilities 102;
Number of Occupations 8;
Total Number of Employees Exposed 3,194
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 80635;
Number of Industries 10;
Total Number of Facilities 343;
Number of Occupations 13;
Total Number of Employees Exposed 16,662;
Total Number of Female Employees Exposed 1,038


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used in fragrances
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
NPIRI* Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015)
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817)

Used in fragrances

RTECS Compound Description:
   Primary Irritant

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