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1,2 - Benzisothiazolin - 3 - one, 1,1 - dioxide, calcium salt

RTECS #: DE4250000

CAS #: 6485-34-3

UPDATE: May 2008 MW: 406.46 MF: C14H10N2O6S2•Ca


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. REVIEWS:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. 1,2 - Benzisothiazol - 3 (2H) - one, 1,1 - dioxide, calcium salt (9CI)
  2. Calcium o - benzosulfimide
  3. Calcium o - benzosulphimide
  4. Calcium 2 - benzosulphimide
  5. Calcium saccharin
  1. Calcium saccharina
  2. Calcium saccharinate
  3. Saccharin calcium
  4. Sulphobenzoic imide calcium salt


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
cytogenetic analysis hamster lung 8 gm/L MUREAV 163,63,1986
unscheduled DNA synthesis rat liver 100 mg/L CNREA8 40,4541,1980


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
International Agency for Research on Cancer (IARC) Cancer Review Animal Inadequate Evidence IMEMDT 73,517,1999
International Agency for Research on Cancer (IARC) Cancer Review Human Inadequate Evidence IMEMDT 73,517,1999
International Agency for Research on Cancer (IARC) Cancer Review Group 3 IMEMDT 73,517,1999
TOXICOLOGY REVIEW
ENTOX* -,750,2005


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X1558;
Number of Industries 2;
Total Number of Facilities 86;
Number of Occupations 3;
Total Number of Employees Exposed 1,017;
Total Number of Female Employees Exposed 777


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY


REFERENCES:

CODEN
REFERENCE
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941-
ENTOX* Encyclopedia of Toxicology: Reference Book, Elsevier, 2005
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972-
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-

RTECS Compound Description:
   Tumorigen
   Mutagen

ALT CAS #: 17105-05-4
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