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Benzenesulfonic acid, 2 - anilino - 5 - (2,4 - dinitroanilino) - , monosodium salt

RTECS #: DB5042500

CAS #: 6373-74-6

UPDATE: October 2002 MW: 452.40 MF: C18H13N4O7S•Na


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. TUMORIGENIC DATA:
  4. OTHER MULTIPLE DOSE DATA:
  5. REVIEWS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. 2 - Anilino - 5 - (2,4 - dinitroanilino) - benzenesulfonic acid, monosodium salt
  2. 2 - Anilino - 5 - (2,4 - dinitroanilino) benzenesulfonic acid sodium salt
  3. 5 - ( (2,4 - Dinitrophenol) amine) - 2 - (phenylamine) - benzenesulfonic acid, monosodium salt
  4. 5 - ( (2,4 - Dinitrophenyl) amino) - 2 - (phenylamino) benzenesulfonic acid monosodium salt
  5. Acid Fast Yellow AG
  6. Acid Fast Yellow E5R
  7. Acid Leather Light Brown G
  8. Acid Orange No. 3
  9. Acid Yellow E
  10. Airedale Yellow E
  11. Amido Yellow E
  12. Amido Yellow EA
  13. Amido Yellow EA - CF
  14. Anthralan Yellow RRT
  15. Benzenesulfonic acid, 5 - ( (2,4 - dinitrophenyl) amino) - 2 - (phenylamino) - , monosodium salt
  16. C.I. 10385
  17. C.I. Acid Orange 3
  18. Coranil Brown H EPS
  19. Derma FUR Yellow RT
  20. Derma Yellow P
  21. Dimacide Yellow N - 5RL
  22. Duasyn Acid Yellow RRT
  23. Elbenyl Orange A - 3RD
  24. Erio Fast Yellow AE
  25. Erio Fast Yellow AEN
  26. Erio Yellow AEN
  27. Erionyl Yellow E - aen
  28. Fast Light Yellow E
  29. Fenalan Yellow E
  1. Heliacid Light Yellow 4R
  2. Intranyl Orange T - 4R
  3. Kiton Fast Yellow A
  4. Lanaperl Yellow Brown GT
  5. Light Fast Yellow ES
  6. Lissamine Fast Yellow AE
  7. Lissamine Fast Yellow AES
  8. Lissamine Yellow AE
  9. Multacid Yellow 3R
  10. Multicuer Brown MPH
  11. NCI - C54911
  12. Nailamide Yellow Brown E - L
  13. Nylocrom Yellow 3R
  14. Nylomine Acid Yellow B - RD
  15. Nylosan Yellow E - 3R
  16. Polan Yellow E - 3R
  17. Sellacid Yellow AEN
  18. Sodium 4 - (2,4 - dinitroanilino) diphenylamine - 2 - sulfonate
  19. Solanile Yellow E
  20. Sulfacid Light Yellow 5RL
  21. Superian Yellow R
  22. Tectilon Orange 3GT
  23. Tertracid Light Yellow 2R
  24. Tetracid Light Yellow 2R
  25. Unitertracid Light Yellow RR
  26. Vondacid Fast Yellow AE
  27. Vondacid Light Yellow AE
  28. Xylene Fast Yellow ES


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
mutation in microorganisms Salmonella typhimurium 100 µg/plate (+enzymatic activation step) EMMUEG 11(Suppl 12),1,1988


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rat 		lowest published toxic dose: 386 gm/kg/2 year- intermittent Tumorigenic: Carcinogenic by RTECS criteria

Kidney, Ureter, and Bladder: Kidney tumors 		NTPTR* NTP-TR-335,1988
oral
rat 		lowest published toxic dose: 386,250 mg/kg/103 week- intermittent Tumorigenic: Carcinogenic by RTECS criteria

Kidney, Ureter, and Bladder: Kidney tumors

Endocrine: Hyperparathyroidism 		NTIS** PB89-216550/AS


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
mouse 		lowest published toxic dose: 65 gm/kg/13 week- intermittent Kidney, Ureter, and Bladder: Other changes NTPTR* NTP-TR-335,1988
oral
rat 		lowest published toxic dose: 97,500 mg/kg/13 week- intermittent Kidney, Ureter, and Bladder: Other changes

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field 		NTPTR* NTP-TR-335,1988


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
International Agency for Research on Cancer (IARC) Cancer Review Animal Limited Evidence IMEMDT 57,121,1993
International Agency for Research on Cancer (IARC) Cancer Review Human Inadequate Evidence IMEMDT 57,121,1993
International Agency for Research on Cancer (IARC) Cancer Review Group 3 IMEMDT 57,121,1993


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X9543;
Number of Industries 1;
Total Number of Facilities 2,258;
Number of Occupations 1;
Total Number of Employees Exposed 22,238;
Total Number of Female Employees Exposed 14,728


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as a dye, pigment and printing ink
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NCI Carcinogenesis Studies (gavage);clear evidence:rat
NTP Carcinogenesis Studies (gavage);clear evidence:rat NTPTR* NTP-TR-335,1988
NCI Carcinogenesis Studies (gavage);no evidence:mouse


REFERENCES:

CODEN
REFERENCE
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987-
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972-
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206-

Used as a dye, pigment and printing ink

RTECS Compound Description:
   Tumorigen
   Mutagen

ALT CAS #: 74968-36-8
 Click Here for Additional Information about RTECS

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