RTECS:DA4797050 The Registry of Toxic Effects of Chemical Substances | CDC/NIOSH

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Benzenemethanol, 4 - hydroxy - alpha - (1 - ( (2 - (4 - hydroxyphenyl) ethyl) amino) ethyl) - , (R*,S*) -

RTECS #: DA4797050

CAS #: 26652-09-5

UPDATE: August 2007 MW: 287.39 MF: C₁₇H₂₁NO₃

NOTE:

TOXICITY DATA HAVE NOT BEEN EVALUATED. OMISSION OF A SUBSTANCE OR NOTATION DOES NOT IMPLY ANY RELIEF FROM REGULATORY RESPONSIBILITY.

TABLE OF CONTENTS:

SYNONYMS:

REPRODUCTIVE EFFECTS DATA:

ACUTE TOXICITY DATA:

REVIEWS:

REFERENCES:

SYNONYMS:

4 - Hydroxy - alpha - (1 - ( (2 - (4 - hydroxyphenyl) ethyl) amino) ethyl) benzenemethanol (R,S) -

Benzyl alcohol, p - hydroxy - alpha - (1 - ( (p - hydroxyphenethyl) amino) ethyl) - , erythro -

DU - 21220

Ritodrina

Ritodrine

Ritodrinium

erythro - p - Hydroxy - alpha - (1 - ( (p - hydroxyphenethyl) amino) ethyl) benzyl alcohol

SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

MUTATION DATA AND REFERENCES:
SYSTEM TEST ROUTE/
ORGANISM/
TISSUE DOSE REFERENCE
N/R N/R N/R N/R

REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
intravenous
rat lowest published toxic dose: 3,000 痢/kg (20 day pregnant) Reproductive: Other effects on female BMMBES 52,128,1994
multiple
woman lowest published toxic dose: 21,040 痢/kg (10-35 week pregnant) Reproductive: Specific developmental abnormalities: Cardiovascular (circulatory) system EOGRAL 59,137,1995

TUMORIGENIC DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
intravenous
rat lowest published toxic dose: 23.6 mg/kg Reproductive: Maternal effects: Uterus, cervix, vagina JPETAB 306,253,2003
oral
rat lowest published toxic dose: 35.1 mg/kg Reproductive: Maternal effects: Uterus, cervix, vagina JPETAB 306,253,2003
oral
rat lowest published toxic dose: 10 mg/kg Behavioral: Analgesia

Behavioral: Change in psychophysiological tests JPETAB 309,414,2004

OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

REVIEWS:
ORGANIZATION STANDARD
REFERENCE

TOXICOLOGY REVIEW
DIMON* 40,258,1994
TOXICOLOGY REVIEW
DIMON* 40,258,1994

STANDARDS AND REGULATIONS:
ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R

NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION STANDARD or SURVEY
REFERENCE

N/R N/R N/R

STATUS IN FEDERAL AGENCIES:
ORGANIZATION
REFERENCE

N/R

REFERENCES:
CODEN
REFERENCE

BMMBES Biochemical Medicine and Metabolic Biology. (Academic Press, Inc., Journal Customer Service, POB 6250, Duluth, MN 55802-0250) V.35- 1986-
DIMON* Disease-a Month (Chicago : Year Book Publishers) V. 24- 1978-
EOGRAL European Journal of Obstetrics, Gynecology and Reproductive Biology. (Elsevier Science Pub. BV, POB 211, 1000 AE Amsterdam, Netherlands) V.3- 1973-
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-

Used to inhibit uterine contractions in pre-term labor

RTECS Compound Description:
Reproductive Effector
Human Data

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