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1,4 - Benzenedicarboxylic acid, dioctyl ester

RTECS #: CZ4110000

CAS #: 4654-26-6

UPDATE: June 1997 MW: 390.62 MF: C24H38O4


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. REFERENCES:

SYNONYMS:

  1. Dioctyl terephthalate
  2. Eastman DOTP Plasticizer
  1. Terephthalic acid, dioctyl ester (6CI,7CI,8CI)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intraperitoneal
mouse 		lethal dose : >3,200 mg/kg N/R FCTOD7 33,971,1995
intraperitoneal
rat 		lethal dose : >3,200 mg/kg N/R FCTOD7 33,971,1995
oral
mouse 		lethal dose (50 percent kill): >3,200 mg/kg N/R FCTOD7 33,971,1995
oral
rat 		lethal dose (50 percent kill): >5 gm/kg N/R FCTOD7 33,971,1995


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rat 		lowest published toxic dose: 51,890 mg/kg/13 week- continuous Liver: Changes in liver weight

Blood: Pigmented or nucleated red blood cells 		FCTOD7 33,971,1995


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
N/R N/R N/R


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
N/R


REFERENCES:

CODEN
REFERENCE
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982-

Used as a plasticizer in polyvinylchloride

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