RTECS:CY9100000 The Registry of Toxic Effects of Chemical Substances | CDC/NIOSH

Search NIOSH | NIOSH Home | NIOSH Topics | Site Index | Databases and Information Resources | NIOSH Products | Contact Us

Benzene, sec - butyl -

RTECS #: CY9100000

CAS #: 135-98-8

UPDATE: February 2004 MW: 134.24 MF: C₁₀H₁₄

NOTE:

TOXICITY DATA HAVE NOT BEEN EVALUATED. OMISSION OF A SUBSTANCE OR NOTATION DOES NOT IMPLY ANY RELIEF FROM REGULATORY RESPONSIBILITY.

TABLE OF CONTENTS:

SYNONYMS:

SKIN AND EYE IRRITATION DATA:

ACUTE TOXICITY DATA:

OTHER MULTIPLE DOSE DATA:

NIOSH DOCUMENTATION AND SURVEILLANCE:

STATUS IN FEDERAL AGENCIES:

REFERENCES:

SYNONYMS:

(1 - Methylpropyl) benzene

2 - Phenylbutane

Benzene, (1 - methylpropyl) - (9CI)

sec - Butylbenzene

SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
eye
rabbit 500 mg/24 hour mild 85JCAE -,36,1986
skin
rabbit 100 mg/24 hour moderate 85JCAE -,36,1986

MUTATION DATA AND REFERENCES:
SYSTEM TEST ROUTE/
ORGANISM/
TISSUE DOSE REFERENCE
N/R N/R N/R N/R

REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

TUMORIGENIC DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
oral
mouse lethal dose (50 percent kill): 8,700 mg/kg N/R VCVGH* -,178,1990
oral
rat lethal dose (50 percent kill): 2,240 無/kg N/R TXAPA9 28,313,1974
oral
rat lethal dose (50 percent kill): 6,300 mg/kg N/R VCVGH* -,178,1990
skin
rabbit lethal dose (50 percent kill): >16 mL/kg N/R TXAPA9 28,313,1974

OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
oral
rat lowest published toxic dose: 742 mg/kg/24 week- intermittent Behavioral: Alteration of classical conditioning VCVGH* -,179,1990
oral
rabbit lowest published toxic concentration: 1,400 mg/kg/4 week- intermittent Liver: Other changes

Kidney, Ureter, and Bladder: Other changes in urine composition

Blood: Changes in spleen VCVGH* -,179,1990

REVIEWS:
ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R

STANDARDS AND REGULATIONS:
ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R

NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X4539;
Number of Industries 2;
Total Number of Facilities 19;
Number of Occupations 2;
Total Number of Employees Exposed 52

STATUS IN FEDERAL AGENCIES:
ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001

REFERENCES:
CODEN
REFERENCE

85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
VCVGH* "Vrednie chemichescie veshestva, galogenproisvodnie uglevodorodov". (Hazardous substances: Galogenated hydrocarbons) Bandman A.L. et al., Chimia, 1990.

RTECS Compound Description:
Primary Irritant

Click Here for Additional Information about RTECS

NIOSH Home | NIOSH Search | Site Index | Topic List | Contact Us