RTECS:CV4550000 The Registry of Toxic Effects of Chemical Substances | CDC/NIOSH

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Benzamide, N - (p - (2 - (dimethylamino) ethoxy) benzyl) - 3,4,5 - trimethoxy - , hydrochloride

RTECS #: CV4550000

CAS #: 554-92-7

UPDATE: November 2004 MW: 424.97 MF: C₂₁H₂₈N₂O₅•ClH

NOTE:

TOXICITY DATA HAVE NOT BEEN EVALUATED. OMISSION OF A SUBSTANCE OR NOTATION DOES NOT IMPLY ANY RELIEF FROM REGULATORY RESPONSIBILITY.

TABLE OF CONTENTS:

SYNONYMS:

ACUTE TOXICITY DATA:

REVIEWS:

NIOSH DOCUMENTATION AND SURVEILLANCE:

REFERENCES:

SYNONYMS:

4 - (2 - Dimethylaminoethoxy) - N - (3,4,5 - trimethoxybenzoyl) benzylamine hydrochloride

N - (p - (2 - (Dimethylamino) ethoxy) benzyl) - 3,4,5 - trimethoxybenzamide hydrochloride

N - (p - (2 - (Dimethylamino) ethoxy) - benzyl) - 3,4,5 - trimethoxybenzamide monohydrochloride

Ro 2 - 9578

Tigan

Tigan hydrochloride

Trimethobenzamide hydrochloride

SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

MUTATION DATA AND REFERENCES:
SYSTEM TEST ROUTE/
ORGANISM/
TISSUE DOSE REFERENCE
N/R N/R N/R N/R

REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

TUMORIGENIC DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
intraperitoneal
mouse lethal dose (50 percent kill): 350 mg/kg Eye: Lacrimation

Lung, Thorax, or Respiration: Dyspnea

Gastrointestinal: Changes in structure or function of salivary glands JPETAB 126,270,1959
intravenous
mouse lethal dose (50 percent kill): 122 mg/kg N/R AIPTAK 174,350,1968
oral
mouse lethal dose (50 percent kill): 1,600 mg/kg N/R AIPTAK 174,350,1968
subcutaneous
mouse lethal dose (50 percent kill): 564 mg/kg N/R AIPTAK 174,350,1968

OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

REVIEWS:
ORGANIZATION STANDARD
REFERENCE

TOXICOLOGY REVIEW
MUREAV 488,151,2001

STANDARDS AND REGULATIONS:
ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R

NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X4629;
Number of Industries 1;
Total Number of Facilities 109;
Number of Occupations 3;
Total Number of Employees Exposed 3,651;
Total Number of Female Employees Exposed 3,453

STATUS IN FEDERAL AGENCIES:
ORGANIZATION
REFERENCE

N/R

REFERENCES:
CODEN
REFERENCE

AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898-
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-

FDA-proprietary drug

RTECS Compound Description:
Drug

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