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| UPDATE: February 2006 | MW: 151.13 | MF: C7H5NO3 |
SYNONYMS:
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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
|
N/R |
N/R
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N/R
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N/R
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MUTATION DATA AND REFERENCES:
SYSTEM TEST
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ROUTE/ | ORGANISM/ TISSUE
DOSE
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REFERENCE
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DNA repair
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Bacillus subtilis
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5 mg/disc
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MUREAV 170,11,1986
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mutation in microorganisms
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Salmonella typhimurium
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1 µmol/plate (+enzymatic activation step)
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MUREAV 58,11,1978
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REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
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N/R
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N/R
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TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
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N/R
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N/R
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ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
|
oral | mouse
lethal dose (50 percent kill): 600 mg/kg
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Behavioral: Altered sleep time (including change in righting reflex) | Lung, Thorax, or Respiration: Dyspnea Gastrointestinal: Changes in structure or function of salivary glands
AFECAT 76(815),65,1983
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OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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N/R |
N/R
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N/R
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N/R
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REVIEWS:
ORGANIZATION
|
STANDARD
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REFERENCE
N/R
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N/R
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N/R
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STANDARDS AND REGULATIONS:
ORGANIZATION
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STANDARD
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REFERENCE
Occupational Exposure Limit - RUSSIA
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short term exposure limit 0.5 mg/m3, Skin, JUN2003
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NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
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STANDARD or SURVEY
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REFERENCE
National Occupational Exposure Survey 1983
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National Occupational Exposure Survey 1983: Hazard Code: X7145 |
Number of Industries 2; Total Number of Facilities 28; Number of Occupations 6; Total Number of Employees Exposed 5,331; Total Number of Female Employees Exposed 883 | |||
STATUS IN FEDERAL AGENCIES:
ORGANIZATION
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REFERENCE
EPA GENETOX PROGRAM 1988, Positive: Histidine reversion-Ames test
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EPA TSCA Section 8(b) CHEMICAL INVENTORY
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REFERENCES:
CODEN
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REFERENCE
AFECAT
|
Annales des Falsifications et de l'Expertise Chimique. (Paris, France) V.53, No.613-No.779,
1960-79.
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MUREAV
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Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1-
1964-
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