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| UPDATE: May 2003 | MW: 210.20 | MF: C8H20N•Br |
SYNONYMS:
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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
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MUTATION DATA AND REFERENCES:
SYSTEM TEST
|
ROUTE/ | ORGANISM/ TISSUE
DOSE
|
REFERENCE
|
N/R
|
N/R
|
N/R
|
N/R
|
| |||
REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
| |||
TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
| |||
ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
intraperitoneal | mouse
lethal dose (50 percent kill): 50 mg/kg
|
N/R
|
NTIS** AD277-689
|
intraperitoneal | mouse
lowest published toxic dose: 50 mg/kg
|
Eye: Mydriasis (pupilliary dilation)
|
FATOAO 50,37,1987
|
intraperitoneal | mouse
lowest published toxic dose: 60 mg/kg
|
Behavioral: Tremor | Behavioral: Change in motor activity (specific assay)
FATOAO 50,37,1987
|
intraperitoneal | rat
lethal dose (50 percent kill): 108 mg/kg
|
N/R
|
PHMGBN 21,256,1980
|
intravenous | cat
lowest published toxic dose: 0.1 mg/kg
|
Eye: Other eye effects | Autonomic Nervous System: Ganglion blocker Vascular: BP lowering not characterized in autonomic section
FATOAO 50,37,1987
|
intravenous | dog
lethal dose (50 percent kill): 55 mg/kg
|
Lung, Thorax, or Respiration: Other changes
|
JPETAB 97,48,1949
|
intravenous | mouse
lethal dose (50 percent kill): 14,200 µg/kg
|
N/R
|
JOPHAN 49,220,1957
|
intravenous | rat
lethal dose (50 percent kill): 63 mg/kg
|
Lung, Thorax, or Respiration: Other changes
|
JPETAB 97,48,1949
|
intravenous | rabbit
lethal dose (50 percent kill): 72 mg/kg
|
Lung, Thorax, or Respiration: Other changes
|
JPETAB 97,48,1949
|
oral | mouse
lethal dose (50 percent kill): >2 gm/kg
|
Lung, Thorax, or Respiration: Other changes
|
JPETAB 97,48,1949
|
subcutaneous | rat
lethal dose (50 percent kill): 200 mg/kg
|
N/R
|
PSEBAA 78,708,1951
|
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OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
| |||
REVIEWS:
ORGANIZATION
|
STANDARD
|
|
REFERENCE
N/R
|
N/R
|
N/R
|
| ||
STANDARDS AND REGULATIONS:
ORGANIZATION
|
STANDARD
|
|
REFERENCE
N/R
|
N/R
|
N/R
|
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NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
|
STANDARD or SURVEY
|
|
REFERENCE
National Occupational Exposure Survey 1983
|
National Occupational Exposure Survey 1983: Hazard Code: X4598 |
 ;Number of Industries 1; Total Number of Facilities 23; Number of Occupations 2; Total Number of Employees Exposed 68; Total Number of Female Employees Exposed 45 | |||
STATUS IN FEDERAL AGENCIES:
ORGANIZATION
|
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REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
|
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REFERENCES:
CODEN
|
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REFERENCE
FATOAO
|
Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939-
|
JOPHAN
|
Journal de Physiologie (Paris). (SPPIF, B.P.22, F-41353 Vineuil, France) V.39- 1946-
|
JPETAB
|
Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E.
Preston St., Baltimore, MD 21202) V.1- 1909/10-
|
NTIS**
|
National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information.
|
PHMGBN
|
Pharmacology: International Journal of Experimental and Clinical Pharmacology. (S. Karger AG,
Postfach CH-4009 Basel, Switzerland) V.1- 1968-
|
PSEBAA
|
Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1903/04-
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