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Ammonium, (2,3 - epoxypropyl) trimethyl - , chloride

RTECS #: BQ3480000

CAS #: 3033-77-0

UPDATE: July 2000 MW: 151.66 MF: C6H14NO•Cl


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. MUTATION DATA:
  4. ACUTE TOXICITY DATA:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. (2,3 - Epoxypropyl) trimethylammonium chloride
  2. G - MAC
  3. Glycidyl - trimethyl - ammonium chloride
  4. Glytac
  1. Glytac A 100
  2. N,N,N - Trimethyloxiranemethanaminium chloride
  3. Oxiranemethanaminium, N,N,N - trimethyl - , chloride (9CI)
  4. Trimethylglycidylammonium chloride


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
eye
rabbit 		50 µL moderate NTIS** OTS0537063


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
cytogenetic analysis rat liver 10 mg/L MUREAV 153,57,1985
unscheduled DNA synthesis rat liver 20 µmol/L MUREAV 245,145,1990
mutation in microorganisms Klebsiella pneumoniae 2 mmol/L (-enzymatic activation step) MUREAV 89,269,1981
other mutation test systems Escherichia coli 33,300 µmol/L MUREAV 231,205,1990
sister chromatid exchange hamster lung 250 µmol/L MUREAV 249,55,1991


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rat 		lethal dose (50 percent kill): 2,300 µL/kg Behavioral: Somnolence (general depressed activity)

Lung, Thorax, or Respiration: Dyspnea 		NTIS** OTS0537063
subcutaneous
mouse 		lethal dose (50 percent kill): 90 mg/kg N/R JCSOA9 -,176,1947
skin
rabbit 		lethal dose : >3,160 µL/kg Behavioral: Muscle weakness

Lung, Thorax, or Respiration: Dyspnea

Skin: After systemic exposure: Dermatitis, other 		NTIS** OTS0537063


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
N/R N/R N/R


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
JCSOA9 Journal of the Chemical Society. (London, UK) 1926-65. For publisher information, see JCPRB4.
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.

RTECS Compound Description:
   Mutagen
   Primary Irritant

Click Here for Additional Information about RTECS

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