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Ammonium, (6 - (dimethylamino) - 3H - xanten - 3 - ylidene) dimethyl - , chloride

RTECS #: BQ1450000

CAS #: 92-32-0

UPDATE: January 1997 MW: 302.83 MF: C17H19N2O•Cl


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. ACUTE TOXICITY DATA:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. C.I. 45005
  2. Methanaminium, N - (6 - (dimethylamino) - 3H - xanthen - 3 - ylidene) - N - methyl - , chloride (9CI)
  3. Methyl pyronin
  4. Pyronine
  5. Pyronine G
  6. Pyronine Y
  1. Pyronine ZH
  2. Pyronin G
  3. Pyronin Y
  4. Pyronin Yellow
  5. Schultz No. 853
  6. Tetramethyl pyronin


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
DNA adduct Escherichia coli 20 µmol/L MUREAV 89,95,1981
DNA repair Bacillus subtilis 2 mg/disc TRENAF 27,153,1976
mutation in microorganisms Escherichia coli 100 ppm/5 hour (-enzymatic activation step) CSHSAZ 12,256,1947
mutation in microorganisms Salmonella typhimurium 80 µg/plate (-enzymatic activation step) TRENAF 27,153,1976
sex chromosome loss and nondisjunction oral
Drosophila melanogaster 		1,000 ppm AMNTA4 87,295,1953


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intravenous
mouse 		lowest published lethal dose: 179 mg/kg Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis) TXAPA9 44,225,1978


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X7179;
Number of Industries 1;
Total Number of Facilities 63;
Number of Occupations 3;
Total Number of Employees Exposed 1,056;
Total Number of Female Employees Exposed 810


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA GENETOX PROGRAM 1988, Positive: B subtilis rec assay; D melanogaster Sex-linked lethal
EPA TSCA Section 8(b) CHEMICAL INVENTORY


REFERENCES:

CODEN
REFERENCE
AMNTA4 American Naturalist. (Univ. of Chicago Press, Journals Div., POB 37005, Chicago, IL 60637) V.1- 1867-
CSHSAZ Cold Spring Harbor Symposia on Quantitative Biology. (Cold Spring Harbor Laboratory, POB 100, Cold Spring Harbor, NY 11724) V.1- 1933-
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
TRENAF Kenkyu Nenpo--Tokyo-toritsu Eisei Kenkyusho. Annual Report of Tokyo Metropolitan Research Laboratory of Public Health. (Tokyo-toritsu Eisei Kenkyusho, 24-1, 3-chome, Hyakunin-cho, Shin-juku-ku, Tokyo 160, Japan) V.1- 1949/50-
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-

Used as a stain

RTECS Compound Description:
   Mutagen

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