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Ammonium, (4 - (p - (dimethylamino) - alpha - phenylbenzylidene) - 2,5 - cyclohexadien - 1 - ylidene) - dimethyl - , oxalate (2:1) , oxalate (1:1)

RTECS #: BQ1190000

CAS #: 2437-29-8

UPDATE: October 1997 MW: 927.10 MF: C46H50N4•C2H2O4•2C2HO4


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. MUTATION DATA:
  4. ACUTE TOXICITY DATA:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Malachite Green Oxalate


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
eye
rabbit 		76 mg severe ARTODN 56,43,1984


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
mutation in microorganisms Salmonella typhimurium 40 µg/plate (-enzymatic activation step) ARTODN 56,43,1984


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
mouse 		lowest published lethal dose: 50 mg/kg N/R ARTODN 56,43,1984
oral
rat 		lethal dose (50 percent kill): 275 mg/kg Behavioral: Change in motor activity (specific assay)

Gastrointestinal: Hypermotility, diarrhea

Gastrointestinal: Other changes 		ARTODN 56,43,1984
skin
rat 		lethal dose : >2 gm/kg N/R ARTODN 56,43,1984


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X2442;
Number of Industries 1;
Total Number of Facilities 6;
Number of Occupations 1;
Total Number of Employees Exposed 112;
Total Number of Female Employees Exposed 41


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974-

Used in aquaculture to control parasitic infections and in industry as a pigment or additive

RTECS Compound Description:
   Agricultural Chemical
   Mutagen
   Primary Irritant

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