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Aluminum (III) silicate (2:1)

RTECS #: BD1450000

CAS #: 1302-76-7

UPDATE: May 2009 MW: 162.05 MF: O5Si•2Al


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. TUMORIGENIC DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. REVIEWS:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. Acicular mullite
  2. Aluminosilcate
  3. Aluminum oxide silicate
  4. Ceramic fibre
  5. Cyanite
  6. Disthene
  7. Kaopolite
  1. Kyanite
  2. Mullite
  3. Oil - dri
  4. Safe - N - Dri
  5. Silicic acid aluminum salt
  6. Valfor


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intrapleural
rat 		lowest published toxic dose: 90 mg/kg Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Lung, Thorax, or Respiration: Tumors 		BJCAAI 28,173,1973


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
mammal (species unspecified) 		lowest published toxic concentration: 10 mg/m3/13 week- intermittent Lung, Thorax, or Respiration: Other changes

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation 		TOXID9 90,214,2006


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
TOXICOLOGY REVIEW
31BYAP -,94,1974


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Occupational Exposure Limit - AUSTRALIA time-weighted average 2 mg(Al)/m3, JUL2008
Occupational Exposure Limit - BELGIUM time-weighted average 2 mg(Al)/m3, MAR2002
Occupational Exposure Limit - FRANCE VME 2 mg(Al)/m3, FEB2006
Occupational Exposure Limit - KOREA time-weighted average 2 mg(Al)/m3, 2006
Occupational Exposure Limit - NEW ZEALAND time-weighted average 2 mg(Al)/m3, JAN2002
Occupational Exposure Limit - NORWAY time-weighted average 2 mg(Al)/m3, JAN1999
Occupational Exposure Limit - RUSSIA time-weighted average 6 mg/m3, JUN2003
Occupational Exposure Limit - SWEDEN time-weighted average 1 mg(Al)/m3, JUN2005
Occupational Exposure Limit - SWITZERLAND MAK- week 2 mg(Al)/m3, DEC2006
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X1426;
Number of Industries 1;
Total Number of Facilities 10;
Number of Occupations 2;
Total Number of Employees Exposed 1,042
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X4779;
Number of Industries 33;
Total Number of Facilities 1,560;
Number of Occupations 34;
Total Number of Employees Exposed 39,077;
Total Number of Female Employees Exposed 727


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
31BYAP "Experimental Lung Cancer: Carcinogenesis and Bioassays, International Symposium, 1974," Karbe, E., and J.F. Park, eds., Springer-Verlag New York, Inc., 1974
BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947-
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981-

Used in metallurgical and glass industries, also used as petroleum-cracking catalyst

NIOSH PROFILE (SILICON AND ITS COMPOUNDS), SRI, 2/77

NIOSH PROFILE (ALUMINUM and ITS COMPOUNDS), SRC, 1/81

RTECS Compound Description:
   Tumorigen

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