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Aloe, pharmaceutical

RTECS #: BC8055000

CAS #: 8001-97-6

UPDATE: September 1995 MW: N/R MF: N/R


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. ACUTE TOXICITY DATA:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. REFERENCES:

SYNONYMS:

  1. AROE (Japanese)
  2. Aloe (Latin)
  1. Aloe, powdered


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
DNA repair Bacillus subtilis 100 gm/L MUREAV 97,81,1982


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
mouse 		lethal dose (50 percent kill): >10 gm/kg Behavioral: Somnolence (general depressed activity)

Gastrointestinal: Hypermotility, diarrhea

Skin and Appendages: Other: Hair 		KSRNAM 14,1403,1980
oral
rat 		lethal dose (50 percent kill): >5 gm/kg Behavioral: Somnolence (general depressed activity)

Gastrointestinal: Hypermotility, diarrhea

Skin and Appendages: Other: Hair 		KSRNAM 14,1403,1980


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: M1046;
Number of Industries 2;
Total Number of Facilities 88;
Number of Occupations 6;
Total Number of Employees Exposed 1,238
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: M1046;
Number of Industries 3;
Total Number of Facilities 1,400;
Number of Occupations 12;
Total Number of Employees Exposed 30,874;
Total Number of Female Employees Exposed 23,491
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X9856;
Number of Industries 1;
Total Number of Facilities 6;
Number of Occupations 1;
Total Number of Employees Exposed 42;
Total Number of Female Employees Exposed 18


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
N/R


REFERENCES:

CODEN
REFERENCE
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960-
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-

FDA-over the counter drug

RTECS Compound Description:
   Drug
   Mutagen
   Natural Product

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