RTECS:AU7358600 The Registry of Toxic Effects of Chemical Substances | CDC/NIOSH

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Adenosine, 2' - deoxy -

RTECS #: AU7358600

CAS #: 958-09-8

UPDATE: January 1997 MW: 251.28 MF: C₁₀H₁₃N₅O₃

NOTE:

TOXICITY DATA HAVE NOT BEEN EVALUATED. OMISSION OF A SUBSTANCE OR NOTATION DOES NOT IMPLY ANY RELIEF FROM REGULATORY RESPONSIBILITY.

TABLE OF CONTENTS:

SYNONYMS:

MUTATION DATA:

ACUTE TOXICITY DATA:

NIOSH DOCUMENTATION AND SURVEILLANCE:

STATUS IN FEDERAL AGENCIES:

REFERENCES:

SYNONYMS:

2' - Deoxyadenosine

Adenine deoxyribonucleoside

Adenine deoxyribose

Adenyldeoxyriboside

Deoxyadenosine

Desoxyadenosine

SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

MUTATION DATA AND REFERENCES:
SYSTEM TEST ROUTE/
ORGANISM/
TISSUE DOSE REFERENCE
cytogenetic analysis hamster fibroblast 500 ľmol/L CYTOAN 49,667,1984
cytogenetic analysis human lymphocyte 6 mmol/L CHROAU 90,239,1984
cytogenetic analysis human leukocyte 3 mmol/L HEREAY 50,139,1963
cytogenetic analysis intraperitoneal
mouse 670 mg/kg NULSAK 17,199,1974
DNA inhibition hamster lung 1 mmol/L BICMBE 64,809,1982
DNA inhibition human HeLa cell 100 ľmol/L BCPCA6 14,205,1965
DNA inhibition mouse Ascites tumor 400 ľmol/L BCPCA6 2,221,1959
DNA inhibition rat liver 10 mmol/L BIORAK 37,787,1972
gene conversion and mitotic recombination Chlamydomonas reinhardi 5 gm/L MUREAV 4,147,1967
mutation in mammalian somatic cells hamster lung 1 mmol/L BICMBE 64,809,1982
mutation in mammalian somatic cells mouse lymphocyte 400 mg/L MUREAV 176,123,1987
phage inhibition capacity Escherichia coli 1 gm/L ZAPOAK 12,583,1972
sister chromatid exchange hamster fibroblast 500 ľmol/L CYTOAN 49,667,1984

REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

TUMORIGENIC DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
intraperitoneal
rat lethal dose (50 percent kill): >800 mg/kg N/R ADTEAS 3,181,1968

OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

REVIEWS:
ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R

STANDARDS AND REGULATIONS:
ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R

NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X1004;
Number of Industries 1;
Total Number of Facilities 35;
Number of Occupations 1;
Total Number of Employees Exposed 115;
Total Number of Female Employees Exposed 64

STATUS IN FEDERAL AGENCIES:
ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY

REFERENCES:
CODEN
REFERENCE

ADTEAS Advances in Teratology. (New York, NY) V.1-5, 1966-72. Discontinued.
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958-
BICMBE Biochimie. (SPPIF, B.P.22, F-41353 Vineuil, France) V.53- 1971-
BIORAK Biochemistry (English Translation). Translation of BIOHAO. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.21- 1956-
CHROAU Chromosoma. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1939-
CYTOAN Cytologia. (Japan Pub. Trading Co. (USA), 1255 Howard St., San Francisco, CA 94103) V.1- 1929-
HEREAY Hereditas (Lund, Sweden). (Gjoerloffsgatan 121, S-261 34 Landskrona, Sweden) V.1- 1947-
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
NULSAK Nucleus (Calcutta). (Dr. A.K. Sharma, Centre of Advanced Studies in Cell and Chromosome Research, Calcutta, 35 Baliygunge Circular Rd., Calcutta 700 019, India) V.1- 1958-
ZAPOAK Zeitschrift fuer Allgemeine Mikrobiologie. (Akademie-Verlag GmbH, Postfach 1233, Berlin DDR-1086 Ger. Dem. Rep.) V.1- 1960-

Used in molecular biology and genetic engineering

RTECS Compound Description:
Mutagen
Human Data

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