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Acetophenone, 4' - methyl -

RTECS #: AM9463000

CAS #: 122-00-9

UPDATE: October 1997 MW: 134.19 MF: C9H10O


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. 1 - (4 - Methylphenyl) ethanone
  2. 1 - Methyl - 4 - acetylbenzene
  3. 4' - Methylacetophenone
  4. Ethanone, 1 - (4 - methylphenyl) - (9CI)
  1. Melilotal
  2. Methyl p - tolyl ketone
  3. p - Acetyltoluene
  4. p - Methylacetophenone


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
skin
human 		1,00% FCTXAV 12,933,1974
skin
rabbit 		500 mg/24 hour mild FCTXAV 12,933,1974


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rat 		lethal dose (50 percent kill): 1,400 mg/kg N/R FCTXAV 12,933,1974


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 83203;
Number of Industries 2;
Total Number of Facilities 38;
Number of Occupations 27;
Total Number of Employees Exposed 5,690
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 83203;
Number of Industries 3;
Total Number of Facilities 325;
Number of Occupations 7;
Total Number of Employees Exposed 3,426;
Total Number of Female Employees Exposed 2,144


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as an intermediate in pharmaceutical and chemical synthesis and used in perfumery
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7.

Used as an intermediate in pharmaceutical and chemical synthesis and used in perfumery

RTECS Compound Description:
   Human Data
   Primary Irritant

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