RTECS:AK4200000 The Registry of Toxic Effects of Chemical Substances | CDC/NIOSH

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Acetoacetanilide

RTECS #: AK4200000

CAS #: 102-01-2

UPDATE: February 2006 MW: 177.22 MF: C₁₀H₁₁NO₂

NOTE:

TOXICITY DATA HAVE NOT BEEN EVALUATED. OMISSION OF A SUBSTANCE OR NOTATION DOES NOT IMPLY ANY RELIEF FROM REGULATORY RESPONSIBILITY.

TABLE OF CONTENTS:

SYNONYMS:

ACUTE TOXICITY DATA:

OTHER MULTIPLE DOSE DATA:

STANDARDS AND REGULATIONS:

NIOSH DOCUMENTATION AND SURVEILLANCE:

STATUS IN FEDERAL AGENCIES:

REFERENCES:

SYNONYMS:

( (Acetoacetyl) amino) benzene

3 - Oxo - N - phenylbutanamide

Acetanilide, 2 - acetyl -

Acetoacetanilid

Acetoacetamidobenzene

Acetoacetylaniline

Acetoacetic acid anilide

Acetoacetic anilide

Acetylacetanilide

Anilid kyseliny acetoctove (Czech)

Butanamide, 3 - oxo - N - phenyl - (9CI)

N - (Acetylacetyl) aniline

N - Phenylacetoacetamide

USAF EK - 1239

alpha - Acetylacetanilide

beta - Ketobutyranilide

SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

MUTATION DATA AND REFERENCES:
SYSTEM TEST ROUTE/
ORGANISM/
TISSUE DOSE REFERENCE
N/R N/R N/R N/R

REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

TUMORIGENIC DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
intraperitoneal
mouse lethal dose (50 percent kill): 300 mg/kg N/R NTIS AD277-689
intraperitoneal
rat lethal dose (50 percent kill): 800 mg/kg Behavioral: Somnolence (general depressed activity)

Vascular: Regional or general arteriolar or venous dilation

Lung, Thorax, or Respiration: Cyanosis NTIS OTS0533572
oral
cat lowest published lethal dose: 500 mg/kg Blood: Methemoglobinemia- Carboxhemoglobinemia NTIS OTS0534808-1
oral
mouse lethal dose (50 percent kill): 3,400 mg/kg N/R GTPZAB 31(1),49,1987
oral
rat lethal dose (50 percent kill): 2,450 mg/kg N/R NTIS OTS0533750
oral
rabbit lethal dose (50 percent kill): 3,925 mg/kg N/R GTPZAB 31(1),49,1987
subcutaneous
rat lethal dose (50 percent kill): 7 gm/kg N/R GTPZAB 31(1),49,1987
skin
guinea pig lethal dose (50 percent kill): >1 gm/kg N/R NTIS OTS0533572

OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
oral
rat lowest published toxic dose: 14,024 mg/kg/14 day- continuous Eye: Other eye effects

Blood: Changes in erythrocyte (RBC) count

Nutritional and Gross Metabolic: Weight loss or decreased weight gain NTIS OTS0533572

REVIEWS:
ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R

STANDARDS AND REGULATIONS:
ORGANIZATION STANDARD
REFERENCE

Occupational Exposure Limit - RUSSIA short term exposure limit 1 mg/m³, JUN2003

NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 84311;
Number of Industries 2;
Total Number of Facilities 53;
Number of Occupations 3;
Total Number of Employees Exposed 1,062
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 84311;
Number of Industries 1;
Total Number of Facilities 50;
Number of Occupations 3;
Total Number of Employees Exposed 1,108

STATUS IN FEDERAL AGENCIES:
ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001

REFERENCES:
CODEN
REFERENCE

GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.

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