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Acetic acid, (ethylenedinitrilo) tetra - , tetrasodium salt

RTECS #: AH5075000

CAS #: 64-02-8

UPDATE: November 2008 MW: 380.20 MF: C10H12N2O8•4Na


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. REVIEWS:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. Aquamoline BC
  2. Aquamollin
  3. Calsol
  4. Celon E
  5. Celon H
  6. Celon IS
  7. Cheelox BF
  8. Cheelox BF - 12
  9. Cheelox BF - 13
  10. Cheelox BF - 78
  11. Cheelox BR - 33
  12. Chelon 100
  13. Chemcolox 200
  14. Chemcolox 240 powder
  15. Complexone
  16. Conigon BC
  17. Distol
  18. Distol 8
  19. EDTA tetrasodium salt
  20. Edathanil tetrasodium
  21. Edetate sodium
  22. Edetic acid tetrasodium salt
  23. Endrate tetrasodium
  24. Ergon
  25. Ethylenebis (iminodiacetic acid) tetrasodium salt
  26. Ethylenediamine sodium tetracetate
  27. Ethylenediaminetetraacetic acid, tetrasodium salt
  28. Glycine, N,N' - 1,2 - ethanediylbis (N - (carboxymethyl) - , tetrasodium salt (9CI)
  29. Hamp - ene 100
  30. Hamp - ene 215
  31. Hamp - ene 220
  32. Hamp - ene Na4
  33. Irgalon
  34. Kalex
  35. Kemplex 100
  36. Komplexon
  37. Metaquest C
  38. N,N' - Ethylenediaminediacetic acid tetrasodium salt
  39. Nervanaid B
  40. Nervanaid B liquid
  41. Nervanid B
  42. Nullapon
  43. Nullapon B
  44. Nullapon BF - 12
  45. Nullapon BF - 78
  46. Nullapon BFC
  1. Nullapon BFC Liquid
  2. Nullapon BFC Xonc
  3. Nullapon BFC Xonc Beads
  4. Perma kleer 100
  5. Perma kleer 50 crystals
  6. Perma kleer tetra CP
  7. Questex
  8. Questex 4
  9. Sequestrene
  10. Sequestrene 30A
  11. Sequestrene Na 4
  12. Sequestrene ST
  13. Sodium EDTA
  14. Sodium ethylenediaminetetraacetate
  15. Sodium ethylenediaminetetraacetic acid
  16. Sodium salt of ethylenediaminetetraacetic acid
  17. Syntes 12A
  18. Syntron B
  19. TST
  20. Tetracemate tetrasodium
  21. Tetracemin
  22. Tetranatrium ethylendiamintetraacetat (Czech)
  23. Tetrasodium (ethylenedinitrilo) tetraacetate
  24. Tetrasodium EDTA
  25. Tetrasodium edetate
  26. Tetrasodium ethylenediaminetetraacetate
  27. Tetrasodium ethylenediaminetetracetate
  28. Tetrasodium salt EDTA
  29. Tetrasodium salt of EDTA
  30. Tetrasodium salt of ethylenediaminetetracetic acid
  31. Tetrine
  32. Trilon B
  33. Tyclarosol
  34. Versene
  35. Versene 100
  36. Versene 220
  37. Versene 67
  38. Versene FE 3
  39. Versene beads
  40. Versene flake
  41. Versene powder
  42. Versene powder tetra sodium
  43. Warkeelate PS - 42
  44. Warkeelate PS - 43
  45. Warkeelate PS - 47
  46. Warkeelate S - 42


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
eye
rabbit 		1,900 µg N/R AAOPAF 48,681,1952
eye
rabbit 		100 mg/24 hour moderate 28ZPAK -,306,1972
skin
rabbit 		500 mg/24 hour moderate 28ZPAK -,306,1972


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intraperitoneal
mouse 		lethal dose (50 percent kill): 330 mg/kg Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis) REPMBN 10,391,1962
intraperitoneal
mouse 		lethal dose (50 percent kill): 350 mg/kg N/R IJTOFN 21,95,2002
intraperitoneal
rat 		lethal dose (50 percent kill): >2 gm/kg N/R IJTOFN 21,95,2002
oral
dog 		lethal dose (50 percent kill): 12 gm/kg N/R IJTOFN 21,95,2002
oral
rat 		lethal dose (50 percent kill): 10 gm/kg N/R IJTOFN 21,95,2002
oral
rabbit 		lethal dose (50 percent kill): 7 gm/kg N/R IJTOFN 21,95,2002


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
TOXICOLOGY REVIEW
IJTOFN 21,95,2002
TOXICOLOGY REVIEW
FEREAC 71,11563,2006


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES: Unsupported RBREV* -,310,1998


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 80223;
Number of Industries 218;
Total Number of Facilities 49,290;
Number of Occupations 128;
Total Number of Employees Exposed 584,676
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 80223;
Number of Industries 293;
Total Number of Facilities 55,714;
Number of Occupations 186;
Total Number of Employees Exposed 1,388,281;
Total Number of Female Employees Exposed 611,582


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as component of soaker-alkali cleaners, and as water softeners, and in viscose rayon
EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-8786;8EHQ-0892-8800
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
28ZPAK "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 1972
AAOPAF AMA Archives of Ophthalmology. (Chicago, IL) V.44(4)-63, 1950-60. For publisher information, see AROPAW.
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
IJTOFN International Journal of Toxicology. (Taylor & Francis, 47 Runway Rd., Suite g, Levittown, PA 19057) V.16- 1997-
RBREV* Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report), Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998
REPMBN Revue d'Epidemiologie, Medecine Sociale et Sante Publique. (Masson Editeur, 120 Blvd. Saint-Germain, F-75280 Paris Cedex O6, France) V.1- 1953-

Used as component of soaker-alkali cleaners, and as water softeners, and in viscose rayon

FDA-over the counter drug

RTECS Compound Description:
   Hormone
   Primary Irritant

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