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| UPDATE: February 2008 | MW: 116.48 | MF: C2H2ClO2•Na |
SYNONYMS:
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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
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MUTATION DATA AND REFERENCES:
SYSTEM TEST
|
ROUTE/ | ORGANISM/ TISSUE
DOSE
|
REFERENCE
|
N/R
|
N/R
|
N/R
|
N/R
|
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REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
| |||
TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
| |||
ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
intraperitoneal | guinea pig
lethal dose (50 percent kill): 115 mg/kg
|
N/R
|
GTPZAB 31(12),53,1987
|
oral | domestic bird
lowest published lethal dose: 100 mg/kg
|
Behavioral: Convulsions or effect on seizure threshold | Behavioral: Coma Gastrointestinal: Other changes
APTOA6 18,179,1961
|
oral | chicken
lethal dose (50 percent kill): 81 mg/kg
|
N/R
|
PCOC** -,1047,1966
|
oral | guinea pig
lethal dose (50 percent kill): 99 mg/kg
|
N/R
|
JIHTAB 23,78,1941
|
oral | mammal (species unspecified)
lowest published lethal dose: 150 mg/kg
|
Behavioral: Muscle contraction or spasticity | Gastrointestinal: Hypermotility, diarrhea Lung, Thorax, or Respiration: Dyspnea
NVTMAF 13,271,1961
|
oral | mouse
lethal dose (50 percent kill): 165 mg/kg
|
N/R
|
JPETAB 86,336,1946
|
oral | rat
lethal dose (50 percent kill): 95 mg/kg
|
N/R
|
JIHTAB 23,78,1941
|
oral | rabbit
lethal dose (50 percent kill): 156 mg/kg
|
N/R
|
PCOC** -,1047,1966
|
subcutaneous | rat
lowest published lethal dose: 60 mg/kg
|
N/R
|
TIHEEC 18,389,2002
|
subcutaneous | rat
lethal dose : 77 mg/kg
|
N/R
|
TIHEEC 18,389,2002
|
subcutaneous | rat
lethal dose : 80 mg/kg
|
Endocrine: Hypoglycemia | Biochemical: Metabolism (intermediary): Other
TIHEEC 18,389,2002
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OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
oral | rat
lowest published toxic dose: 5,400 mg/kg/90 day- intermittent
|
Liver: Changes in liver weight | Kidney, Ureter, and Bladder: Changes in bladder weight Blood: Changes in leukocyte (WBC) count
TXCYAC 67,171,1991
|
| |||
REVIEWS:
ORGANIZATION
|
STANDARD
|
|
REFERENCE
N/R
|
N/R
|
N/R
|
| ||
STANDARDS AND REGULATIONS:
ORGANIZATION
|
STANDARD
|
|
REFERENCE
Occupational Exposure Limit - RUSSIA
|
short term exposure limit 0.5 mg/m3, Skin, JUN2003
|
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NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
|
STANDARD or SURVEY
|
|
REFERENCE
N/R
|
N/R
|
N/R
|
| ||
STATUS IN FEDERAL AGENCIES:
ORGANIZATION
|
|
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
|
Used for control of a wide range of annual weeds in seedling stage
|
EPA TSCA Section 8(d) unpublished health/safety studies
|
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
|
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REFERENCES:
CODEN
|
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REFERENCE
APTOA6
|
Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher
information, see PHTOEH
|
GTPZAB
|
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see
MTPEEI
|
JIHTAB
|
Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For
publisher information, see AEHLAU.
|
JPETAB
|
Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E.
Preston St., Baltimore, MD 21202) V.1- 1909/10-
|
NVTMAF
|
Nordisk Veterinaermedicin Danske Udgave. (Copenhagen, Denmark)
|
PCOC**
|
Pesticide Chemicals Official Compendium, Association of the American Pesticide Control
Officials, Inc., 1966. (Topeka, KS)
|
TIHEEC
|
Toxicology and Industrial Health. (Princeton Scientific Pub. Co., POB 2155, Princeton, NJ
08540) V.1- 1985-
|
TXCYAC
|
Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973-
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