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Acetamide, 2,2' - ( (2 - hydroxyethyl) imino) bis (N - (alpha,alpha - dimethylphenethyl) - N - methyl -

RTECS #: AC3325000

CAS #: 126-27-2

UPDATE: September 1999 MW: 467.72 MF: C28H41N3O3


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. ACUTE TOXICITY DATA:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. REFERENCES:

SYNONYMS:

  1. 2,2' - ( (2 - Hydroxyethyl) imino) bis (N - (alpha,alpha - dimethylphenethyl) - N - methylacetamide)
  2. 2,2' - ( (2 - Hydroxyethyl) imino) bis (N - (1,1 - dimethyl - 2 - phenylethyl) - N - methylacetamide)
  3. 2 - Di (N - methyl - N - phenyl - tert - butyl - carbamoylmethyl) aminoethanol
  4. Acetamide, 2,2' - (2 - hydroxyethyl) imino) bis (N - (1,1 - dimethylphenylethyl) - N - methyl - (9CI)
  5. Betalgil
  6. FH 099
  7. Mucaine
  8. Mucoxin
  9. Mutesa
  10. Muthesa
  11. N,N - Bis (N - methyl - N - phenyl - tert - butylacetamido) - beta - hydroxyethylamine
  1. Oxaine
  2. Oxetacaine
  3. Oxethacaina (Italian)
  4. Oxethacaine
  5. Oxethazaine
  6. Oxethazine
  7. Stomacain
  8. Tepilta
  9. Topicain
  10. WY 806


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
sex chromosome loss and nondisjunction Aspergillus nidulans 1 mg/L MUREAV 26,159,1974


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intraperitoneal
mouse 		lethal dose (50 percent kill): 27 mg/kg N/R GMITAB 134,642,1975
intraperitoneal
rat 		lethal dose (50 percent kill): 30 mg/kg N/R GMITAB 134,642,1975
oral
mouse 		lethal dose (50 percent kill): 1 gm/kg N/R NIIRDN -,283,1995
oral
rat 		lethal dose (50 percent kill): 1 gm/kg N/R NIIRDN -,283,1995
subcutaneous
mouse 		lethal dose (50 percent kill): 58 mg/kg N/R GMITAB 134,642,1975


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 82267;
Number of Industries 2;
Total Number of Facilities 838;
Number of Occupations 5;
Total Number of Employees Exposed 29,119
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 82267;
Number of Industries 1;
Total Number of Facilities 32;
Number of Occupations 2;
Total Number of Employees Exposed 1,056;
Total Number of Female Employees Exposed 490


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
N/R


REFERENCES:

CODEN
REFERENCE
GMITAB Gazzetta Medica Italiana. (Turin, Italy) V.95-142, 1936-83.
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan)

RTECS Compound Description:
   Drug
   Mutagen

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