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NIOSH - National Institute for Occupational Safety and Health

Draft Document for Scientific Peer Review:

Asbestos and Other Mineral Fibers: A Roadmap for Scientific Research

 

The National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention (NIOSH, CDC) has authored a White Paper entitled Asbestos and Other Mineral Fibers: A Roadmap for Scientific Research (Roadmap). This document has been determined by NIOSH to be an Influential Scientific Assessment according to Office of Management and Budget (OMB) guidelines issued pursuant to Section 515 of Public Law 106-554, commonly known as the "Data Quality Act" (codified at 44 USC 3504(d)(1) and 3516). To meet the OMB requirements for peer review of Influential Scientific Assessments, peer reviewers have been identified, and a peer review process has been developed. The overall goal of the peer review is to enhance the quality and credibility of Agency recommendations by ensuring that the scientific and technical work underlying these recommendations receives appropriate review by independent scientific and technical experts. The peer review charge described below was developed in accordance with OMB guidelines, is consistent with NIOSH peer review practice, and is meant to ensure that credible and appropriate science is used in the development of its worker protection recommendations for asbestos and other mineral fibers exposures in the workplace. In addition to peer review, NIOSH welcomes comments and input on the Roadmap from interested stakeholders and the public at large.

Charge to the Peer Reviewers

The goals of the Roadmap are to (1) describe the current NIOSH policies for asbestos and other mineral fibers and their basis, (2) describe the scientific uncertainties associated with asbestos and other mineral fibers pertinent to worker protection policies, and (3) describe research needs and directions to reduce the scientific uncertainties and develop appropriate worker protection policies. The charge to the Peer Reviewers is to objectively review the Roadmap and substantive comments received from stakeholders and the public to determine whether

  • the current NIOSH policies for asbestos and other mineral fibers have been adequately  described;
  • the key issues and scientific uncertainties impacting worker health protection policies for asbestos and other mineral fibers have been clearly identified,
  • the identified research needs and research approaches would likely lead to greater scientific understanding of the health effects of asbestos and other mineral fibers, and
  • the results of the identified research needs and research approaches would appropriately inform the development of more effective worker protection policies for asbestos and other mineral fibers.

Reviewers of this Roadmap will address the five questions below:

  1. Is the hazard identification and discussion of health effects for asbestos and mineral fibers a reasonable reflection of the current understanding of the evidence in the scientific literature?
  2. Is the discussion of the current understanding of the analytical issues and the research needs for analysis of asbestos and mineral fibers appropriate and relevant?
  3. Is the discussion of the current understanding of the epidemiological issues and the research needs for understanding the health effects of asbestos and mineral fibers appropriate and relevant?
  4. Is the discussion of the current understanding of the toxicological issues and the research needs for understanding the health effects of asbestos and mineral fibers appropriate and relevant?
  5. Is the discussion of the path forward appropriate and relevant and is the ultimate vision a reasonable outcome for the proposed research strategy for asbestos and mineral fibers?

Public Meeting
A public meeting will be held in May 2007, in Washington, DC, as a forum for scientists and representatives of government agencies, industry, labor, and other stakeholders to discuss the Roadmap, ask questions, and provide oral and written comments on the Roadmap. The meeting will be open to the public, limited only by the space available. An announcement of the meeting (date, location) will be published in the Federal Register.

Stakeholder and Other Public Input and Comments
We request that public comments be submitted to the NIOSH Docket Office by May 31, 2007. Please return your written comments either by mail (to Diane Miller, NIOSH Docket Office, Robert A. Taft Laboratories, Mail Stop C-34, 4676 Columbia Parkway, Cincinnati, Ohio 45226) or electronically via e-mail (to nioshdocket@cdc.gov.) All electronic comments should be formatted as Microsoft Word. Please make reference to docket number NIOSH-099.

Time Frame for Review
All substantive public comments received in the NIOSH Docket Office by May 31, 2007 will be provided to the Peer Reviewers by June 30, 2007. The Peer Reviewers will develop individual reports that take into consideration the substantive stakeholder comments. Reports are expected to be received by NIOSH by August 15, 2007. NIOSH will then consider and respond to the comments received before issuing a final Roadmap.

List of Reviewers

William N. Rom, MD, MPH
New York University

Ann Wylie, Ph.D.
University of Maryland

Brooke Mossman, Ph.D.
University of Vermont

Morton Lippmann, Ph.D.
New York University

David Michaels, Ph.D., MPH
George Washington University

Franklin Mirer, Ph.D.
Hunter College

William Eschenbacher, MD
Group Health Associates

Brad Van Gosen, MS
US Geological Survey

L. Christine Oliver, MD, MPH
Harvard School of Medicine