NORA Construction Sector Strategic Goals
927ZEXN - Genetic Modulation of Worker Susceptibility to Noise-Induced Hearing LossStart Date: 4/1/2008
End Date: 9/30/2009
Principal Investigator (PI)Name: Rickie Davis
Funded By: NIOSH
Primary Goal AddressedNone
Secondary Goal AddressedNone
Attributed to Construction50%
The purpose of this project is 1) to update the molecular biology capabilities of the DART laboratories and 2) determine if genetic factors can be determined which identify workers who have an increased susceptibility to noise-induced hearing loss. Partnering with the Department of the Navy, volunteers will provide biological samples which will be tested for genetic variation of seven pre-selected genes. These genes have been shown to code for proteins important for hearing. This project is based on seed money provided by the National Office of Public Health Genomics and will end on September 30, 2009.
The ultimate goal of this research is to reduce the incidence of NIHL by integrating genetic tests into worker safety programs. This would allow susceptible workers to receive additional resources (e.g. advanced training, high-tech hearing protection or additional monitoring) to reduce the occurrence of NIHL.
This effort will be successful if the resulting publications result in further research into the genetic bases of individual susceptibility to noise-induced hearing loss. These efforts should be measurable in citation reports.