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Isocyanates and human health: multistakeholder information needs and research priorities.

Authors
Lockey-JE; Redlich-CA; Streicher-R; Pfahles-Hutchens-A; Hakkinen-PJ; Ellison-GL; Harber-P; Utell-M; Holland-J; Comai-A; White-M
Source
J Occup Environ Med 2015 Jan; 57(1):44-51
NIOSHTIC No.
20045501
Abstract
Objectives: To outline the knowledge gaps and research priorities identified by a broad base of stakeholders involved in the planning and participation of an international conference and research agenda workshop on isocyanates and human health held in Potomac, Maryland, in April 2013. Methods: A multimodal iterative approach was used for data collection including preconference surveys, review of a 2001 consensus conference on isocyanates, oral and poster presentations, focused break-out sessions, panel discussions, and postconference research agenda workshop. Results: Participants included representatives of consumer and worker health, health professionals, regulatory agencies, academic and industry scientists, labor, and trade associations. Conclusions: Recommendations were summarized regarding knowledge gaps and research priorities in the following areas: worker and consumer exposures; toxicology, animal models, and biomarkers; human cancer risk; environmental exposure and monitoring; and respiratory epidemiology and disease, and occupational health surveillance.
Keywords
Isocyanates; Models; Exposure-limits; Risk-factors; Animals; Biomarkers; Cancer; Monitoring-systems; Epidemiology; Respiratory-system-disorders
Contact
James E. Lockey, MD, MS, Department of Environmental Health, Division of Occupational and Environmental Medicine, University of Cincinnati College of Medicine, 3223 Eden Ave, Cincinnati, OH 45267
CODEN
JOEMFM
Publication Date
20150101
Document Type
Journal Article
Email Address
lockeyje@ucmail.uc.edu
Fiscal Year
2015
NTIS Accession No.
NTIS Price
Issue of Publication
1
ISSN
1076-2752
NIOSH Division
DART
Source Name
Journal of Occupational and Environmental Medicine
State
OH; CT; DC; MD; AZ; NY; MI
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