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Accelerated annual decline in Fev1 among Norwegian aluminum workers.

Authors
Soyseth-V; Bakke-B; Henneberger-PK; Kongerud-J
Source
Am J Respir Crit Care Med 2014 May; 189(Meeting Abstracts):A5100
NIOSHTIC No.
20044511
Abstract
In a longitudinal study we have compared the annual decline in lung function between potroom operators in seven Norwegian aluminum plants (index group) and a reference group that comprises employees in a road construction company, a roller factory, and a rim factory. The index group and the reference group consisted of 4,774 and 537 employees, respectively. They were followed up annually using spirometry and a respiratory questionnaire. The index group differed from the reference group by having proportionately fewer females (20% versus 26%) and a lower mean age at inclusion (29.2 years, sd=11.6 versus 35.0 years, sd=12.4). The mean forced expiratory volume in one second (FEV1) and forced vital capacity (FVC) at inclusion were greater for index participants, with values of FEV1=4.35 (sd=0.85) and FVC=5.28 (sd=0.98) L in the index group and FEV1=4.01 (sd=0.80) and FVC=5.03 (sd=0.97) L among the references. Current smokers accounted for approximately half of each group, with 2,196 (53 %) and 294 (56 %) in the index group and among the references, respectively. The subjects were followed-up for 10 years. The mean annual declines in FEV1 (dFEV1) and FVC (dFVC) by study group and smoking status. After controlling for height, gender, smoking habits and age at inclusion in linear mixed regression models, aluminum plant workers had an accelerated annual decline in FEV1 (20.2 ml/year, 95% CI: 6.5 to 33.8) but not FVC (-6.5 ml/year, 95% CI: -20.3 to 7.1). In conclusion, our data indicate that aluminum potroom workers had an increased risk of pulmonary obstructive disease compared to workers in otherwise comparable settings.
Keywords
Respiratory-system-disorders; Pulmonary-system-disorders; Pulmonary-function; Lung-disorders; Lung-function; Aluminum-compounds; Employee-exposure; Aluminum-industry; Industrial-factory-workers; Spirometry; Pulmonary-function-tests; Vital-capacity; Smoking; Humans; Men; Women; Airway-obstruction
Contact
V. Soyseth, Akershus University Hospital, Lorenskog, Norway
CODEN
AJCMED
CAS No.
7429-90-5
Publication Date
20140501
Document Type
Abstract
Fiscal Year
2014
NTIS Accession No.
NTIS Price
Identifying No.
M062014
ISSN
1073-449X
NIOSH Division
DRDS
Source Name
American Journal of Respiratory and Critical Care Medicine
State
WV
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