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Deposition of man-made fibers in human respiratory airway casts.

Authors
Su-W-C; Cheng-YS
Source
J Aerosol Sci 2009 Mar; 40(3):270-284
NIOSHTIC No.
20044499
Abstract
New experiments of fiber deposition in the human respiratory airway were conducted by delivering aerosolized man-made fibers (TiO2 and glass) into two different human respiratory airway casts at three inspiratory flow rates. Fiber deposition patterns and regional deposition efficiencies in the airway casts were studied and compared with previously published results acquired from carbon fiber. The results showed that very few small momentum fibers (TiO2 and glass fibers) were deposited in the airway casts, which is significantly different from the results found for the large momentum fiber (carbon fiber). The fiber deposition pattern and deposition efficiency in the two airway casts were similar in both trend and magnitude, and all of the data revealed an overall continuity between fiber materials. Empirical models were proposed based on the experimental data acquired for estimating the fiber's regional deposition efficiency in the human respiratory airway.
Keywords
Aerosols; Aerosol-particles; Fibrous-dusts; Inhalants; Airborne-fibers; Air-sampling; Exposure-levels; Risk-factors; Asbestos-fibers; Asbestos-dust; Particulates; Analytical-processes; Computer-models; Computer-software; Computers; Models; Air-flow; Simulation-methods; Author Keywords: Man-made fiber; Human airway; Deposition pattern; Deposition effciency
CODEN
JALSB7
Publication Date
20090301
Document Type
Journal Article
Funding Type
Grant
Fiscal Year
2009
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-003900
Issue of Publication
3
ISSN
0021-8502
Source Name
Journal of Aerosol Science
State
NM
Performing Organization
Lovelace Biomedical & Environmental Research, Albuquerque, New Mexico
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