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Household solid fuel use, body mass index, and pulmonary function in an urban population in Shanghai, China.

Authors
Lee-M-S; Hang-J-Q; Zhang-F-Y; Zheng-B-Y; Su-L; Zhao-Y; Christiani-DC
Source
Am J Respir Crit Care Med 2012 May; 185(Meeting Abstracts):A1752
NIOSHTIC No.
20044458
Abstract
Rationale: The use of solid fuel has been associated with respiratory diseases such as acute respiratory infections (ARIs), chronic obstructive pulmonary disease (COPD), and lung cancer, but little has been known to date on lung function in an urban population. We investigated the association between household solid fuel exposure and lung function in a densely populated district in urban Shanghai, China. We further examined effect modification by body mass index (BMI). Methods: Spirometry was performed in 12,506 subjects, aged 18 and over, residing the Putuo District in Shanghai, China, in a cross-sectional survey. Exposure to solid fuel use at home was assessed by administered questionnaire, estimating duration and total amount of solid fuel use at home during the lifetime. Results: After adjusting for confounders, exposure to household solid fuel was associated with reduced forced expiratory volume in 1 sec (FEV1) [beta = 1.3; 95% confidence interval (CI) -2.02 to -0.57] and forced vital capacity (FVC) [beta = 3.5; 95% CI -4.18 to -2.74], as the percentage of the predicted value. Trends towards decreased pulmonary function measures were seen for longer duration and greater amount of household fuel use at home, in the highest compared with lowest tertile (P values for trend < 0.001). We observed significant decline in percent predicted FEV1 and FVC across increase in BMI in association with in-home solid fuel exposure. Conclusions: Our data suggest that in-home solid fuel exposure is associated with impaired lung function in an urban population, and BMI modifies this association, implying obese subjects may be more susceptible to in-home fuel exposure.
Keywords
Fuels; Respiratory-system-disorders; Pulmonary-system-disorders; Lung-disorders; Airway-obstruction; Lung-cancer; Lung-function; Humans; Body-burden; Weight-factors; Weight-measurement; Spirometry; Health-surveys; Questionnaires; Exposure-assessment; Pulmonary-function; Pulmonary-function-tests
Contact
M.-S. Lee, Harvard School of Public Health, Boston, MA
CODEN
AJCMED
Publication Date
20120501
Document Type
Abstract
Email Address
mslee@hsph.harvard.edu
Funding Type
Grant
Fiscal Year
2012
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-T42-CCT-110421
ISSN
1073-449X
Source Name
American Journal of Respiratory and Critical Care Medicine
State
MA
Performing Organization
Harvard School of Public Health, Boston, Massachusetts
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