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The effects of impact vibration on peripheral blood vessels and nerves.

Authors
Krajnak-KM; Waugh-S; Johnson-C; Miller-GR; Xu-X; Warren-C; Dong-RG
Source
Ind Health 2013 Nov-Dec; 51(6):572-580
NIOSHTIC No.
20043580
Abstract
Research regarding the risk of developing hand-arm vibration syndrome after exposure to impact vibration has produced conflicting results. This study used an established animal model of vibration-induced dysfunction to determine how exposure to impact vibration affects peripheral blood vessels and nerves. The tails of male rats were exposed to a single bout of impact vibration (15 min exposure, at a dominant frequency of 30 Hz and an unweighted acceleration of approximately 345 m/s(2)) generated by a riveting hammer. Responsiveness of the ventral tail artery to adrenoreceptor-mediated vasoconstriction and acetylcholine-mediated re-dilation was measured ex vivo. Ventral tail nerves and nerve endings in the skin were assessed using morphological and immunohistochemical techniques. Impact vibration did not alter vascular responsiveness to any factors or affect trunk nerves. However, 4 days following exposure there was an increase in protein-gene product (PGP) 9.5 staining around hair follicles. A single exposure to impact vibration, with the exposure characteristics described above, affects peripheral nerves but not blood vessels.
Keywords
Exposure-levels; Risk-factors; Hand-tools; Hand-injuries; Vibration-exposure; Vibration; Animals; Laboratory-animals; Nerve-function; Nerves; Author Keywords: Cardiovascular disorders; muscloskeletal disorders; Sensorineural disorders; animal model
CODEN
INHEAO
Publication Date
20131101
Document Type
Journal Article
Email Address
ksk12cdc.gov
Fiscal Year
2014
NTIS Accession No.
NTIS Price
Issue of Publication
6
ISSN
0019-8366
NIOSH Division
HELD
Source Name
Industrial Health
State
WV
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