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Serum bisphenol-A concentration and sex hormone levels in men.

Authors
Zhou-Q; Miao-M; Ran-M; Ding-L; Bai-L; Wu-T; Yuan-W; Gao-E; Wang-J; Li-G; Li-D-K
Source
Fertil Steril 2013 Aug; 100(2):478-482
NIOSHTIC No.
20043531
Abstract
OBJECTIVE: To evaluate the association between serum bisphenol-A (BPA) concentration and sex hormone levels in men. DESIGN: Cross-sectional study. SETTING: Not applicable. PATIENT(S): A total of 290 men with or without BPA exposure in the workplace. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Serum sex hormone levels. RESULT(S): After adjustment for potential confounders using linear regression, increasing serum BPA concentration was statistically significantly associated with [1] decreased androstenedione levels, [2] decreased free testosterone levels, [3] decreased free androgen index, and [4] increased sex hormone-binding globulin levels. Comparison of hormone levels between workers exposed and unexposed to BPA showed similar associations. CONCLUSION(S): Exposure to a high BPA level may impact sex hormone levels in men.
Keywords
Humans; Men; Age-groups; Hormones; Sex-factors; Exposure-levels; Biphenyls; Blood-analysis; Blood-cells; Author Keywords: Bisphenol-A; BPAl endocrine disruption; men; sex hormones
Contact
Jintao Wang, M.D., Ph.D., Department of Epidemiology, School of Public Health, Shanxi Medical University, Taiyuan, People's Republic of China
CODEN
FESTAS
Publication Date
20130801
Document Type
Journal Article
Email Address
wangjt59@163.com
Funding Type
Grant
Fiscal Year
2013
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-007580; M122013
Issue of Publication
2
ISSN
0015-0282
Source Name
Fertility and Sterility
State
CA
Performing Organization
Kaiser Foundation Research Institute
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