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The association between obstructive sleep apnea and hypertension by race/ethnicity in a nationally representative sample.

Authors
Sands-Lincoln-M; Grandner-M; Whinnery-J; Keenan-BT; Jackson-N; Gurubhagavatula-I
Source
J Clin Hypertens 2013 Aug; 15(8):593-599
NIOSHTIC No.
20043372
Abstract
The association between obstructive sleep apnea (OSA) and hypertension by race/ethnicity has not been well characterized in a national sample. Adult participants in the 2007-2008 National Health and Nutrition Examination Survey were reviewed by self-report of sleep apnea diagnosis, snorting, gasping or stopping breathing during sleep, and snoring to derive whether OSA was probable (pOSA). Multivariable logistic regression determined whether pOSA predicted hypertension in the overall cohort, and by body mass index (BMI) group and ethno-racial strata. pOSA predicted hypertension in several groups: (1) Within BMI strata, there was a significant association among overweight individuals [odds ratio [OR], 1.82; 95% confidence interval [CI], 1.26-2.62); (2) In race/ethnicity subgroups, the association was significant among Hispanic/Latinos (OR, 1.69; 95% CI, 1.13-2.53) and whites (OR, 1.40; 95% CI, 1.07-1.84); (3) In models stratified by both race/ethnicity and BMI, pOSA predicted hypertension among overweight black/African Americans (OR, 4.74; 95% CI, 1.86-12.03), overweight whites (OR, 1.65; 95% CI, 1.06-2.57), and obese Hispanic/Latino participants (OR, 2.01; 95% CI, 1.16-3.49). A simple, self-report tool for OSA was strongly associated with hypertension, and may serve as a potential future opportunity for OSA diagnosis.
Keywords
Sleep-disorders; Hypertension; Sociological-factors; Humans; Men; Women; Body-weight; Weight-factors
Contact
Megan Sands-Lincoln, PhD, MPH, Center for Sleep and Circadian Neurobiology, Perelman School of Medicine, University of Pennsylvania, 3624 Market Street, Suite 205, Philadelphia, PA 19104
CODEN
JCHYEM
Publication Date
20130801
Document Type
Journal Article
Email Address
megsands@mail.med.upenn.edu
Funding Type
Grant
Fiscal Year
2013
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-009149; M112013
Issue of Publication
8
ISSN
0748-450X
Source Name
Journal of Clinical Hypertension
State
PA
Performing Organization
University of Pennsylvania
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