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Retrospective assessment of exposure to chemicals for a microelectronics and business machine manufacturing facility.

Authors
Fleming-DA; Woskie-SR; Jones-JH; Silver-SR; Luo-L; Bertke-SJ
Source
J Occup Environ Hyg 2014 May; 11(5):292-305
NIOSHTIC No.
20043364
Abstract
A retrospective exposure assessment was performed for use in a health outcomes study of a facility manufacturing circuit boards, business machines and other equipment during the years 1969-2002. A matrix was developed identifying chemical use by department-year based on company-provided information. Use of six chemical agents (fiberglass, lead, methylene chloride, methyl chloroform, perchloroethylene and trichloroethylene) and six chemical classes (acid-base, aromatic hydrocarbons, chlorinated hydrocarbons, other hydrocarbons, chlorofluorocarbons and metals), and general (including unspecified) chemicals was identified. The matrix also contained an assignment for each department-year categorizing the potential for use of chemicals as negligible, intermittent/incidental, or routine. These department-based exposure matrix data were combined with work history data to provide duration of potential chemical use for workers. Negligible, intermittent/incidental or routine extent-of-chemical-use categories comprised 42.6%, 39.4% and 17.9% respectively, of total person-years of employment. Cumulative exposure scores were also developed, representing a relative measure of the cumulative extent of potential exposure to the six chemical agents, six chemical classes, and general (including unspecified) chemicals. Additionally, the study period was divided into manufacturing eras showing trends in chemical use, and showing that process use of trichloroethylene and methylene chloride ended in the mid-1980s and the mid-1990s, respectively. This approach may be useful in other assessments addressing a variety of chemicals, and with data constraints common to retrospective chemical exposure studies.
Keywords
Exposure-assessment; Electronic-equipment; Electronics-industry; Computer-equipment; Solvents; Heavy-metals; Acids; Metals; Hydrocarbons; Fluorocarbons; Epidemiology; Statistical-analysis; Author Keywords: occupational exposure; circuit board manufacture; substrate production; exposure
Contact
Donald A. Fleming, 4676 Columbia Parkway, MS R-14, Cincinnati, OH 45226
CODEN
JOEHA2
CAS No.
7439-92-1; 75-09-2; 71-55-6; 127-18-4; 79-01-6
Publication Date
20140501
Document Type
Journal Article
Email Address
dmf9@cdc.gov
Fiscal Year
2014
NTIS Accession No.
NTIS Price
Identifying No.
M112013
Issue of Publication
5
ISSN
1545-9624
NIOSH Division
DSHEFS
Priority Area
Manufacturing
Source Name
Journal of Occupational and Environmental Hygiene
State
OH; MA; VA
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