Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

NIOSHTIC-2 Publications Search

Search Results

Occupational mortality associated with inflammatory bowel disease in the United States 1984-1998.

Authors
Sonnenberg-A; Walker-JT
Source
Inflamm Bowel Dis 2012 Jul; 18(7):1249-1253
NIOSHTIC No.
20043145
Abstract
BACKGROUND: The occurrence of Crohn's disease (CD) and ulcerative colitis (UC) is shaped by environmental influences. Many such environmental risk factors vary potentially with occupational exposure. We used a large national database to study the occupational variation of mortality associated with CD and UC. METHODS: The National Occupational Mortality Surveillance database contains data from the death certificate linked with information about the occupation and industry of each deceased individual. Deaths were grouped by gender, ethnicity, disease type, occupation, and industry. Mortality by occupation and industry were expressed as age-adjusted proportional mortality ratio. RESULT: A total of 3110 inflammatory bowel disease (IBD) patients were included in the present analysis. IBD mortality was low among blue collar workers and high among white collar workers. It was low among farming occupations, manufacturing occupations, and manual laborers. It was high among secretaries, professionals, sales workers, homemakers, managerial occupations, and teachers. There was a strong correlation between the occupational distribution of CD and UC that applied to men and women alike. The overall distribution among different industries corroborated the patterns observed with respect to the occupational distribution. CONCLUSIONS: The correlations between the occupational distribution of CD and UC support the contention that environmental influences shape the occurrence of both diseases. Such influence must vary by occupation and, to a lesser extent, also by industry. It must be similar for both types of IBD.
Keywords
Humans; Men; Women; Adolescents; Age-groups; Intestinal-tissue; Epidemiology; Environmental-factors; Environmental-exposure; Risk-factors; Exposure-levels; Statistical-analysis; Gastrointestinal-system; Gastrointestinal-system-disorders; Author Keywords: Crohn's disease; environmental risk factors; epidemiology; industry; occupation; occupational mortality statistics; proportional mortality ratio; ulcerative colitis
Contact
Amnon Sonnenberg, MD, MSc, Portland VA Medical Center, P3-GI, 3710 SW US Veterans Hospital Road, Portland, OR 97239
CODEN
IBDNBG
Publication Date
20120701
Document Type
Journal Article
Email Address
sonnenbe@ohsu.edu
Fiscal Year
2012
NTIS Accession No.
NTIS Price
Issue of Publication
7
ISSN
1078-0998
NIOSH Division
DSHEFS
Source Name
Inflammatory Bowel Diseases
State
OR; OH
TOP