Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

NIOSHTIC-2 Publications Search

Search Results

Long-term respiratory health effects in textile workers.

Authors
Lai-PS; Christiani-DC
Source
Curr Opin Pulm Med 2013 Mar; 19(2):152-157
NIOSHTIC No.
20042989
Abstract
PURPOSE OF REVIEW: Over 60 million people worldwide work in the textile or clothing industry. Recent studies have recognized the contribution of workplace exposures to chronic lung diseases, in particular chronic obstructive pulmonary disease (COPD). Early studies in textile workers have focused on the relationship between hemp or cotton dust exposure and the development of a syndrome termed byssinosis. The purpose of this review is to evaluate the effect of long-term exposure to organic dust in textile workers on chronic respiratory disease in the broader context of disease classifications, such as reversible or irreversible obstructive lung disease (i.e. asthma or COPD), and restrictive lung disease. RECENT FINDINGS: Cessation of exposure to cotton dust leads to improvement in lung function. Recent animal models have suggested a shift in the lung macrophage:dendritic cell population ratio as a potential mechanistic explanation for persistent inflammation in the lung due to repeated cotton dust-related endotoxin exposure. Other types of textile dust, such as silk, may contribute to COPD in textile workers. SUMMARY: Textile dust-related obstructive lung disease has characteristics of both asthma and COPD. Significant progress has been made in the understanding of chronic lung disease due to organic dust exposure in textile workers.
Keywords
Humans; Men; Women; Clothing; Workers; Work-environment; Exposure-levels; Risk-factors; Lung-disease; Pulmonary-disorders; Pulmonary-function; Pulmonary-system; Pulmonary-system-disorders; Textile-workers; Cotton-dust; Hemp; Byssinosis; Organic-dusts; Respiratory-system-disorders; Animals; Laboratory-animals; Author Keywords: byssinosis; chronic obstructive pulmonary disease; endotoxin; lung; textile; vegetable dust
Contact
Peggy S. Lai, MD, Pulmonary and Critical Care Unit, Department of Medicine, Bulfinch 148, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114
CODEN
COPMFY
Publication Date
20130301
Document Type
Journal Article
Email Address
pslai@hsph.harvard.edu
Funding Type
Grant
Fiscal Year
2013
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-002421; B20130805; M082013
Issue of Publication
2
ISSN
1070-5287
Source Name
Current Opinion in Pulmonary Medicine
State
MA
Performing Organization
Harvard University
TOP