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Work-related peak flow and asthma symptoms in a damp building.

Authors
White-SK; Cox-Ganser-JM; Benaise-LG; Kreiss-K
Source
Occup Med 2013 Jun; 63(4):287-290
NIOSHTIC No.
20042528
Abstract
BACKGROUND: Working in damp conditions is associated with asthma, but few studies have used objective testing to document work-related patterns.AimsTo describe the relationship of peak flow measurements to work-related asthma (WRA) symptoms and WRA among occupants in a damp office building. METHODS: At the beginning of the study, all workers were offered a questionnaire and methacholine challenge testing. Participants were then instructed to perform serial spirometry using handheld spirometers five times per day over a 3 week period. Peak flow data were analysed using OASYS-2 software. We calculated the area between the curves (ABC score) using hours from waking. We considered a score >5.6 L/min/h to be indicative of a work-related pattern. RESULTS: All 24 employees participated in the questionnaire. Seven participants (29%) reported physician-diagnosed asthma with onset after starting work in the building. Almost two-thirds (63%) of participants reported at least one lower respiratory symptom (LRS) occurring one or more times per week in the last 4 weeks. Twenty-two (92%) consented to participate in serial spirometry. Fourteen participants had adequate quality of serial spirometry, five of whom had ABC scores >5.6, ranging from 5.9-23.0. Of these five, two had airways responsiveness, three had current post-hire onset physician-diagnosed asthma and four reported work-related LRS. CONCLUSIONS: We found evidence of work-related changes in serial peak flows among some occupants of an office building with a history of dampness. Serial peak flows may be a useful measure to determine WRA in office settings.
Keywords
Respiratory-system-disorders; Bronchial-asthma; Work-environment; Office-workers; Health-surveys; Questionnaires; Worker-health; Methacholines; Medical-screening; Diagnostic-tests; Spirometry; Environmental-contamination; Indoor-environmental-quality; Airway-resistance; Author Keywords: Asthma; dampness; lower respiratory symptoms; OASYS; serial spirometry
Contact
S. K. White, Division of Respiratory Disease Studies, NIOSH, 1095 Willowdale Rd, MS-2800, Morgantown, WV 26505, USA
CODEN
OCMEE8
Publication Date
20130601
Document Type
Journal Article
Email Address
sqg8@cdc.gov
Fiscal Year
2013
NTIS Accession No.
NTIS Price
Identifying No.
B20130520
Issue of Publication
4
ISSN
0962-7480
NIOSH Division
DRDS
Source Name
Occupational Medicine
State
WV
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