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Cumulative risk assessment (CRA): transforming the way we assess health risks.

Authors
Williams-PRD; Dotson-GS; Maier-A
Source
Environ Sci Technol 2012 Oct; 46(20):10868-10874
NIOSHTIC No.
20041852
Abstract
Human health risk assessments continue to evolve and now focus on the need for cumulative risk assessment (CRA). CRA involves assessing the combined risk from coexposure to multiple chemical and nonchemical stressors for varying health effects. CRAs are broader in scope than traditional chemical risk assessments because they allow for a more comprehensive evaluation of the interaction between different stressors and their combined impact on human health. Future directions of CRA include greater emphasis on local-level community-based assessments; integrating environmental, occupational, community, and individual risk factors; and identifying and implementing common frameworks and risk metrics for incorporating multiple stressors.
Keywords
Risk-factors; Exposure-levels; Risk-analysis; Models; Biomarkers
CODEN
ESTHAG
Publication Date
20121016
Document Type
Journal Article
Email Address
pwilliams@erisksciences.com.
Fiscal Year
2013
NTIS Accession No.
NTIS Price
Identifying No.
B20121218D
Issue of Publication
20
ISSN
0013-936X
NIOSH Division
EID
Source Name
Environmental Science and Technology
State
CO; OH
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