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Leukemia among male construction workers in California, 1988-2007.

Authors
Luckhaupt-SE; Deapen-D; Cress-R; Schumacher-P; Shen-R; Calvert-GM
Source
Leuk Lymphoma 2012 Nov; 53(11):2228-2236
NIOSHTIC No.
20041696
Abstract
A total of 18,708 male cases of leukemia from the California Cancer Registry, including 1,703 cases usually employed in construction, were each matched with up to five controls from the same source who were diagnosed with cancers not thought to be related to exposures common in construction. Compared to other workers, construction workers were found to have a significantly elevated risk for all leukemia combined (morbidity odds ratio [MOR] = 1.14, 95% confidence interval [CI] = 1.08, 1.20), acute lymphocytic leukemia (ALL) (MOR = 1.30, 95% CI = 1.07, 1.58), acute myeloid leukemia (AML) (MOR = 1.15, 95% CI = 1.03, 1.27) and chronic myeloid leukemia (CML) (MOR = 1.25, 95% CI = 1.09, 1.44). Among the different construction occupations, the highest MOR for all leukemia was among carpet installers (MOR = 1.99, 95% CI = 1.16, 3.44), followed by plumbers (MOR = 1.28, 95% CI = 1.03, 1.59) and laborers (MOR = 1.26, 95% CI = 1.12, 1.42). Other associations were limited to specific construction occupations, leukemia subtypes and/or racial/ethnic groups. These associations should be further studied with more in-depth exposure assessment.
Keywords
Surveillance-programs; Cancer; Cancer-rates; Leukemogenesis; Men; Construction; Construction-industry; Construction-workers; Employee-exposure; Employee-health; Risk-factors; Lymphatic-cancer; Myeloid-tissue; Morbidity-rates; Floors; Plumbers; Epidemiology; Statistical-analysis; Author Keywords: Cancer; leukemia; surveillance; construction; occupational; floors; floor coverings
Contact
Sara E. Luckhaupt, MD, MPH, NIOSH, DSHEFS, 4676 Columbia Parkway, MS R-17, Cincinnati, OH 45226, USA
CODEN
LELYEA
Publication Date
20121101
Document Type
Journal Article
Email Address
sluckhaupt@cdc.gov
Fiscal Year
2013
NTIS Accession No.
NTIS Price
Identifying No.
B20121218A
Issue of Publication
11
ISSN
1042-8194
NIOSH Division
DSHEFS
Priority Area
Construction
Source Name
Leukemia & Lymphoma
State
OH; CA
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