Evaluation of silicosis in response to highest task silica exposure with imputed values where no measurements were made.
Grimsley-F; Rice-C; Ayer-H; Clark-S; Succop-P; Rinsky-R
American Industrial Hygiene Conference and Exposition, May 20-25, 2000, Orlando, Florida. Fairfax, VA: American Industrial Hygiene Association, 2000 May; :80
More than one million workers are exposed annually to silica in the workplace. The purpose and specific aims of this study were to investigate ways to estimate silica exposure in unsampled tasks and to evaluate the relationship between highest task silica exposure imputed and the development of silicosis. Data from the North Carolina Dusty Trades, a unique resource for exposure-response studies of the effects of silica exposure, is the basis for the study. Three methods of imputation were used. The methods were estimating exposures based on the mean exposure at sampled commodity-specific tasks, the lower bound of the 95% confidence interval of the median of commodity-specific tasks, and maximum likelihood estimate. The three imputation methods are described and presented. The results of this study indicate that the highest task-related silica exposure is related to the development of silicosis with an odds ratio of 2.22 and is statistically significant (p=0.001). These results can serve as a guide to changes in sampling methods and targeted control techniques that should be implemented to decrease disease in the workplace.
Exposure-assessment; Epidemiology; Silica-dusts; Silicon-compounds; Silicosis; Respiratory-system-disorders; Pulmonary-system-disorders; Lung-disorders; Analytical-processes; Employee-exposure; Industrial-exposures; Occupational-exposure; Task-performance; Information-retrieval-systems; Dose-response; Dust-exposure; Dust-sampling; Analytical-methods; Sampling-methods; Dust-control
American Industrial Hygiene Conference and Exposition, May 20-25, 2000, Orlando, Florida
University of Cincinnati