Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

NIOSHTIC-2 Publications Search

Search Results

Neurodegenerative causes of death among retired National Football League players.

Authors
Lehman-EJ; Hein-MJ; Baron-SL; Gersic-CM
Source
Neurology 2012 Nov; 79(19):1970-1974
NIOSHTIC No.
20041462
Abstract
Objective: To analyze neurodegenerative causes of death, specifically Alzheimer disease (AD), Parkinson disease, and amyotrophic lateral sclerosis (ALS), among a cohort of professional football players. Methods: This was a cohort mortality study of 3,439 National Football League players with at least 5 pension-credited playing seasons from 1959 to 1988. Vital status was ascertained through 2007. For analysis purposes, players were placed into 2 strata based on characteristics of position played: nonspeed players (linemen) and speed players (all other positions except punter/kicker). External comparisons with the US population used standardized mortality ratios (SMRs); internal comparisons between speed and nonspeed player positions used standardized rate ratios (SRRs). Results: Overall player mortality compared with that of the US population was reduced (SMR 0.53, 95% confidence interval [CI] 0.48-0.59). Neurodegenerative mortality was increased using both underlying cause of death rate files (SMR 2.83, 95% CI 1.36-5.21) and multiple cause of death (MCOD) rate files (SMR 3.26, 95% CI 1.90-5.22). Of the neurodegenerative causes, results were elevated (using MCOD rates) for both ALS (SMR 4.31, 95% CI 1.73-8.87) and AD (SMR 3.86, 95% CI 1.55-7.95). In internal analysis (using MCOD rates), higher neurodegenerative mortality was observed among players in speed positions compared with players in nonspeed positions (SRR 3.29, 95% CI 0.92-11.7). Conclusions: The neurodegenerative mortality of this cohort is 3 times higher than that of the general US population; that for 2 of the major neurodegenerative subcategories, AD and ALS, is 4 times higher. These results are consistent with recent studies that suggest an increased risk of neurodegenerative disease among football players.
Keywords
Neurological-reactions; Neurological-system; Epidemiology; Statistical-analysis; Mortality-data; Mortality-rates; Mortality-surveys; Athletes; Sports-injuries; Neurological-diseases; Demographic-characteristics
Contact
Everett J. Lehman, National Institute for Occupational Safety and Health, Division of Surveillance, Hazard Evaluations and Field Studies, Cincinnati, OH 45226
CODEN
NEURAI
Publication Date
20121106
Document Type
Journal Article
Email Address
elehman@cdc.gov
Fiscal Year
2013
NTIS Accession No.
NTIS Price
Identifying No.
B09262012
Issue of Publication
19
ISSN
0028-3878
NIOSH Division
DSHEFS
Source Name
Neurology
State
OH
TOP