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Determinants of chlorpyrifos exposures and urinary 3,5,6-trichloro-2-pyridinol levels among termiticide applicators.

Authors
Hines-CJ; Deddens-JA
Source
Arbete och Halsa 2001 Jun; 2001(10):435-437
NIOSHTIC No.
20041295
Abstract
Introduction: Chlorpyrifos is an organophosphorus insecticide widely used in the United States to control structural termites. It is metabolized in the liver to chlorpyrifos oxon, which is further detoxified to 3,5,6-trichloro-2-pyridinol (TCP) and excreted into the urine. The mean urine elimination half-life of TCP in humans after administration of oral and dermal doses of chlorpyrifos has been estimated to be 26.9 h (2). The aim of this study was to identify significant determinants of chlorpyrifos exposure and urinary TCP that could be used to build predictive exposure models.
Keywords
Epidemiology; Exposure-assessment; Pest-control; Pesticides; Pesticide-residues; Insecticides; Organo-phosphorus-compounds; Organo-phosphorus-pesticides; Employee-exposure; Models; Urinalysis; Urine-chemistry; Analytical-models
Contact
C. J. Hines, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, R-14, Cincinnati, OH 45226, USA
CAS No.
2921-88-2; 6515-38-4
Publication Date
20010601
Document Type
Abstract
Email Address
chines@cdc.gov
Editors
Hagsberg-M; Knave-B; Lillienberg-L; Westberg-H
Fiscal Year
2001
NTIS Accession No.
NTIS Price
ISBN No.
9789170456077
Issue of Publication
10
ISSN
0346-7821
NIOSH Division
DSHEFS
Source Name
Arbete och Halsa (X2001 - exposure assessment in epidemiology and practice, June 10-13, 2001, Göteborg, Sweden)
State
OH
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