Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

NIOSHTIC-2 Publications Search

Search Results

Quantification of respirable, thoracic, and inhalable quartz exposures by FT-IR in personal impactor samples from construction sites.

Authors
Bello-D; Virji-MA; Kalil-AJ; Woskie-SR
Source
Appl Occup Environ Hyg 2002 Aug; 17(8):580-590
NIOSHTIC No.
20041040
Abstract
The classification of quartz as a group 1 human carcinogen by the International Agency for Research on Cancer (IARC) highlights the need to develop a method to assess quartz exposures in the thoracic and inhalable particle size fractions to supplement the current method for the respirable size fraction. Heavy and highway construction operations can produce high respirable quartz exposures, but inhalable and thoracic exposures have not previously been well characterized. These larger particle size fractions may well contribute to the elevated cancers of the buccal cavity, throat, and GI tract in occupational cohorts of construction workers. A description is provided of the application of FT-IR for quartz analysis of personal cascade impactor air samples collected from highway construction sites. Separate calibration curves were generated for each stage of the four-stage personal impactor by using the impactor to sample quartz dust (Min-U-Sil 5 and Min-U-Sil 30) in an aerosol-generating loop. In addition, three separate calibration curves were generated using filters spiked with bulk Min-U-Sil 5, Min-U-Sil 30, and SRM 1878a (a respirable standard from NIST). The results showed that bulk Min-U-Sil 5 and SRM 1878a calibrations were identical and accurately estimated the respirable quartz fraction. Bulk Min-U-Sil 30 underestimated quartz in stages 1, 2, and 3 by 46 percent, 38 percent, and 18 percent, respectively. Using a respirable standard (bulk Min-U-Sil 5 or SRM 1878a) to quantify the larger particle sizes underestimated quartz in stages 1, 2, and 3 by 73 percent, 72 percent, and 63 percent, respectively. Until a standard reference material for quartz is developed for the larger particle sizes, the method described here, with some modifications, can be used to provide estimates of these biologically relevant particle size fractions. The results of this study also reaffirmed the need to collect narrow ranges of particle size in order to minimize quantification errors, since the FT-IR and XRD instrumental response is particle size-dependent.
Keywords
Construction; Construction-industry; Construction-materials; Construction-workers; Respirable-dust; Quartz-dust; Silica-dusts; Thorax; Inhalants; Carcinogens; Humans; Particulate-sampling-methods; Particulate-dust; Exposure-assessment; Sampling-methods; Road-construction; Spectrographic-analysis; Cancer; Air-sampling; Airborne-dusts; Air-contamination; Environmental-pollution; Standards; Quality-standards; Quantitative-analysis; Analytical-instruments; Author Keywords: Construction; Exposure Assessment; Fourier Transform Infrared Spectrophotometry (FT-IR); Min-U-Sil; Personal Impactor; Quartz; Respirable; Thoracic; Inhalable; Silica; Size-Selective Sampling
CODEN
AOEHE9
CAS No.
14808-60-7; 7631-86-9
Publication Date
20020801
Document Type
Journal Article
Funding Type
Cooperative Agreement; Construction
Fiscal Year
2002
NTIS Accession No.
NTIS Price
Identifying No.
Cooperative-Agreement-Number-U60-CCU-317202
Issue of Publication
8
ISSN
1047-322X
Priority Area
Construction
Source Name
Applied Occupational and Environmental Hygiene
State
MA; DC
Performing Organization
The Center to Protect Workers' Rights
TOP