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Prospective study of hepatic, renal, and haematological surveillance in hazardous materials firefighters.

Authors
Kales-SN; Polyhronopoulos-GN; Aldrich-JM; Mendoza-PJ; Suh-JH; Christiani-DC
Source
Occup Environ Med 2001 Feb; 58(2):87-94
NIOSHTIC No.
20041033
Abstract
OBJECTIVES: To evaluate possible health effects related to work with hazardous materials as measured by end organ effect markers in a large cohort over about 2 years, and in a subcohort over 5 years. METHODS: Hepatic, renal, and haematological variables were analysed from 1996-98 in hazardous materials firefighters including 288 hazardous materials technicians (81%) and 68 support workers (19%). The same end organ effect markers in a subcohort of the technicians were also analysed (n=35) from 1993-98. Support workers were considered as controls because they are also firefighters, but had a low potential exposure to hazardous materials. RESULTS: During the study period, no serious injuries or exposures were reported. For the end organ effect markers studied, no significant differences were found between technicians and support workers at either year 1 or year 3. After adjustment for a change in laboratory, no significant longitudinal changes were found within groups for any of the markers except for creatinine which decreased for both technicians (p<0.001) and controls (p<0.01). CONCLUSIONS: Health effects related to work are infrequent among hazardous materials technicians. Haematological, hepatic, and renal testing is not required on an annual basis and has limited use in detecting health effects in hazardous materials technicians.
Keywords
Humans; Men; Women; Hazardous-materials; Hazards; Age-groups; Fire-fighters; Hematology; Kidneys; Kidney-function; Liver; Liver-function; Organs; Author Keywords: hazardous materials; firefighters; medical surveillance
Contact
S. N. Kales, Occupational Medicine, Department of Medicine, The Cambridge Hospital, 1493 Cambridge Street, Cambridge, MA 02139
CODEN
OEMEEM
Publication Date
20010201
Document Type
Journal Article
Email Address
stefokali@aol.com
Funding Type
Grant
Fiscal Year
2001
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-K01-OH-000156; Grant-Number-R01-OH-003729
Issue of Publication
2
ISSN
1351-0711
Source Name
Occupational and Environmental Medicine
State
MA
Performing Organization
Occupational Medicine, Cambridge Hospital, Cambridge, Massachusetts
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