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Epidemiological aspects of occupational lead poisoning.

Authors
Landrigan-PJ; Baker-EL
Source
J UOEH 1983 Mar; 5(Suppl):145-155
NIOSHTIC No.
20041026
Abstract
In recent years a major concern in occupational medicine has been to define the toxicity of lead at lower levels of exposure. Investigations conducted since 1970 have demonstrated that lead causes hematologic, neurologic, and renal impairment in lead workers at exposure levels that previously were considered to be safe. In this report the authors describe three recent epidemiological studies of occupational lead exposure. Their purpose in each instance was to evaluate dose-response relationships between blood lead levels and lead toxicity, particularly at lower levels of occupational lead exposure. In this study evidence was found for clinical, hematological, neurological and renal impairment in lead workers many of whom had blood lead levels between 40 and 80 gu/dl. Such findings suggest that blood lead levels in lead workers should not exceed 40 ug/dl, a value already more than two standard deviations above the mean for adult males in the United States.
Keywords
Lead-compounds; Toxic-effects; Renal-toxicity; Exposure-levels; Epidemiology; Blood-samples; Blood-tests; Blood-cells; Humans; Men; Kidney-function; Kidney-disorders; Kidneys; Physiopathology; Metallurgy
CODEN
JOUOD4
CAS No.
7439-92-1
Publication Date
19830320
Document Type
Journal Article
Fiscal Year
1983
NTIS Accession No.
NTIS Price
ISSN
0387-821X
NIOSH Division
DSHEFS; OD
Source Name
Journal of University of Occupational and Environmental Health
State
NC; OH; GA; MA
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