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Disruptive effects of prefeeding and haloperidol administration on multiple measures of food-maintained behavior in rats.

Authors
Hayashi-Y; Wirth-O
Source
Behav Processes 2012 Mar; 89(3):314-318
NIOSHTIC No.
20040621
Abstract
Four rats responded under a choice reaction-time procedure. At the beginning of each trial, the rats were required to hold down a center lever for a variable duration, release it following a high- or low-pitched tone, and press either a left or right lever, conditionally on the tone. Correct choices were reinforced with a probability of .95 or .05 under blinking or static houselights, respectively. After performance stabilized, disruptive effects of free access to food pellets prior to sessions (prefeeding) and intraperitoneal injection of haloperidol were examined on multiple behavioral measures (i.e., the number of trials completed, percent of correct responses, and reaction time). Resistance to prefeeding depended on the probability of food delivery for the number of trials completed and reaction time. Resistance to haloperidol, on the other hand, was not systematically affected by the probability of food delivery for all dependent measures.
Keywords
Laboratory-animals; Animals; Reaction-rates; Behavior; Behavioral-tests; Behavioral-testing; Author Keywords: Behavioral momentum theory; Choice reaction-time procedure; Haloperidol; Lever press; Prefeeding; Rats
Contact
Yusuke Hayashi, University of Kansas, Life Span Inst Parsons, 2601 Gabriel, Parsons, KS 67357 USA
CODEN
BPRODA
Publication Date
20120301
Document Type
Journal Article
Email Address
yhayashi@ku.edu
Fiscal Year
2012
NTIS Accession No.
NTIS Price
Identifying No.
B04252012
Issue of Publication
3
ISSN
0376-6357
NIOSH Division
HELD
Source Name
Behavioural Processes
State
WV
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