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Approaches for calculating power for case-cohort studies.

Authors
Kim-MY; Xue-X; Du-Y
Source
Biometrics 2006 Sep; 62(3):929-933
NIOSHTIC No.
20040340
Abstract
An approach for determining the power of a case-cohort study for a single binary exposure variable and a low failure rate was recently proposed by Cai and Zeng (2004, Biometrics 60, 1015-1024). In this article, we show that computing power for a case-cohort study using a standard case-control method yields nearly identical levels of power. An advantage of the case-control approach is that existing sample size software can be used for the calculations. We also propose an additional formula for computing the power of a case-cohort study for the situation when the event is not rare.
Keywords
Epidemiology; Group-dynamics; Exposure-levels; Exposure-limits; Carcinogens; Statistical-analysis; Risk-factors; Environmental-exposure; Models; Mathematical-models; Analytical-models; Molecular-biology; Humans; Men; Women; Radiation-exposure; Radiation; Author Keywords: Case-cohort design; Power; Sample size
Contact
Mimi Y. Kim, Division of Biostatistics, Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York 10461
CODEN
BIOMB6
Publication Date
20060901
Document Type
Journal Article
Email Address
mikim@aecom.yu.edu
Funding Type
Grant
Fiscal Year
2006
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-008087
Issue of Publication
3
ISSN
0006-341X
Source Name
Biometrics
State
NY
Performing Organization
Albert Einstein College of Medicine
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