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Harmonization of measurement strategies for exposure to manufactured nano-objects: report of a workshop.

Authors
Brouwer-D; Berges-M; Virji-MA; Fransman-W; Bello-D; Hodson-L; Gabriel-S; Tielemans-E
Source
Ann Occup Hyg 2012 Jan; 56(1):1-9
NIOSHTIC No.
20040040
Abstract
The present paper summarizes the outcome of the discussions at the First International Scientific Workshop on Harmonization of Strategies to Measure and Analyze Exposure to (Manufactured) Nano-objects in Workplace Air that was organized and hosted by the Netherlands Organization for Applied Scientific Research (TNO) and the Institute for Occupational Safety and Health of the German Social Accident Insurance (IFA) (Zeist, The Netherlands, December 2010). It reflects the discussions by 25 international participants in the area of occupational (nano) exposure assessment from Europe, USA, Japan, and Korea on nano-specific issues related to the three identified topics: (i) measurement strategies; (ii) analyzing, evaluating, and reporting of exposure data; and (iii) core information for (exposure) data storage. Preliminary recommendations were achieved with respect to (i) a multimetric approach to exposure assessment, a minimal set of data to be collected, and basic data analysis and reporting as well as (ii) a minimum set of contextual information to be collected and reported. Other issues that have been identified and are of great interest include (i) the need for guidance on statistical approaches to analyze time-series data and on electron microscopy analysis and its reporting and (ii) the need for and possible structure of a (joint) database to store and merge data. To make progress in the process of harmonization, it was concluded that achieving agreement among researchers on the preliminary recommendations of the workshop is urgent.
Keywords
Nanotechnology; Measurement-equipment; Analytical-instruments; Analytical-processes; Exposure-assessment; Air-sampling; Air-sampling-equipment; Air-sampling-techniques; Sampling; Sampling-equipment; Particulate-sampling-methods; Particulates; Data-processing; Information-processing; Information-retrieval-systems; Information-systems; Microscopic-analysis; Statistical-analysis; Author Keywords: core information; database; exposure; harmonization; nanoparticles; strategy
Contact
Derk Brouwer, TNO, The Netherlands Organization for Applied Scientific Research, Research Group Quality & Safety, PO Box 360, 3700 AJ, Zeist, Netherlands
CODEN
AOHYA3
Publication Date
20120101
Document Type
Journal Article
Email Address
dick.brouwer@tno.nl
Fiscal Year
2012
NTIS Accession No.
NTIS Price
Identifying No.
B12212011
Issue of Publication
1
ISSN
0003-4878
NIOSH Division
DRDS; EID
Priority Area
Manufacturing
Source Name
Annals of Occupational Hygiene
State
WV; MA; OH
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