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Pilot study for the investigation of personal breathing zone and dermal exposure using levels of polycyclic aromatic compounds (PAC) and PAC metabolites in the urine of hot-mix asphalt paving workers.

Authors
Osborn-LV; Snawder-JE; Olsen-LD; Kriech-AJ; Cavallari-JM; Herrick-RF; McClean-MD; Blackburn-GR
Source
Polycycl Aromat Compd 2011 Aug; 31(4):173-200
NIOSHTIC No.
20039688
Abstract
As part of the design of a comprehensive study of hot-mix asphalt paving workers to investigate the relative contribution of personal breathing zone and dermal exposures to polycyclic aromatic compounds, a two-part pilot (Phase I) was performed. The pilot study was important to examine the sources of exposure, the chemical nature of these exposures, and their biological relevance through analysis of biomarkers in urine. Existing, modified, and new sampling and analytical techniques, used in concert with each other, were evaluated to help design the full-scale study (Phase II). Although subject numbers were limited, the air, dermal, and urine sampling, analytical results and field experience provided valuable guidance in the design and implementation of Phase II. An overview of methods used and developed from this study is provided. More details of those methods selected for Phase II are presented in complementary manuscripts. Results of Phase II will be the subject of future publications.
Keywords
Construction; Construction-materials; Asphalt-cements; Asphalt-concretes; Asphalt-fumes; Construction-workers; Road-construction; Road-surfacing; Breathing; Breathing-atmospheres; Breathing-zone; Dermatology; Skin; Skin-exposure; Skin-irritants; Polycyclic-aromatic-hydrocarbons; Biological-effects; Biomarkers; Urinalysis; Sampling; Sampling-equipment; Sampling-methods; Analytical-instruments; Analytical-processes; Metabolites; Inhalants; Inhalation-studies; Author Keywords: asphalt paving; dermal; inhalation; polycyclic aromatic compounds
Contact
Linda V. Osborn, Heritage Research Group, 7901 West Morris Street, Indianapolis, Indiana 46231, USA
CODEN
PARCEO
Publication Date
20110801
Document Type
Journal Article
Email Address
linda.osborn@heritage-enviro.com
Fiscal Year
2011
NTIS Accession No.
NTIS Price
Identifying No.
B10122011
Issue of Publication
4
ISSN
1040-6638
NIOSH Division
DART
Source Name
Polycyclic Aromatic Compounds
State
IN; OH; MA; PA
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