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Study design and methods to investigate inhalation and dermal exposure to polycyclic aromatic compounds and urinary metabolites from asphalt paving workers: research conducted through partnership.

Authors
Kriech-AJ; Osborn-LV; Snawder-JE; Olsen-LD; Herrick-RF; Cavallari-JM; McClean-MD; Blackburn-GR
Source
Polycycl Aromat Compd 2011 Aug; 31(4):243-269
NIOSHTIC No.
20039562
Abstract
Innovations in science may require crossing traditional boundaries between industry, unions, government, and academia. While such collaborations have the potential to be highly beneficial and productive, opportunities for such collaborations are often missed due to some of the inherent challenges. This collaborative research effort demonstrates an example of how a successful partnership can optimize the ability to answer complicated scientific questions. Specifically, these researchers collaborated to investigate inhalation and dermal exposures to polycyclic aromatic compounds and related urinary metabolites in hot-mix asphalt paving workers. Reported here are details of the partnership process used to create the study design, the review processes, and details of the analytical methodologies employed to help attain the study goals related to the identification of the nature, source, pathway, and biological relevance of exposure during hot-mix asphalt paving operations. The actual results of the study are being prepared for future publications.
Keywords
Analytical-processes; Asphalt-fumes; Asphalt-industry; Biological-effects; Biological-factors; Biological-monitoring; Biological-systems; Chemical-hypersensitivity; Chemical-properties; Ethylenes; Inhalants; Inhalation-studies; Metabolic-activation; Metabolites; Oils; Organic-chemicals; Organic-compounds; Propylenes; Sampling; Sampling-methods; Skin; Skin-exposure; Skin-irritants; Skin-sensitivity; Urine-chemistry; Work-areas; Work-performance; Worker-health; Workplace-studies; Author Keywords: asphalt; dermal; fumes; inhalation; paving; polycyclic aromatic compounds; urinary metabolites
Contact
Linda V. Osborn, Heritage Research Group, 7901 West Morris Street, Indianapolis, Indiana 4623
CODEN
PARCEO
Publication Date
20110801
Document Type
Journal Article
Email Address
linda.osborn@heritage-enviro.com
Fiscal Year
2011
NTIS Accession No.
NTIS Price
Issue of Publication
4
ISSN
1040-6638
NIOSH Division
DART
Source Name
Polycyclic Aromatic Compounds
State
OH; IN
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