Validation and optimization of a solid sorbent dynamic personal air sampling method for aldehydes.
Shen-Y; Que Hee-S
American Industrial Hygiene Conference and Exposition, May 9-15, 1998, Atlanta, Georgia. Fairfax, VA: American Industrial Hygiene Association, 1998 May; :45
A solid sorbent personal dynamic air sampling method for aldehydes using chemisorption through reaction with O-(2,3,4,5,6-pentafluorobenzyl) hydroxylamine hydrochloride (PFBHA) has been developed and several aldehydes validated. The aim of this study was to validate this method for formaldehyde, to test the influence of temperature on sampling efficiency, and also to optimize desorption efficiency. Formaldehyde is an animal carcinogen and a suspected human carcinogen. There is need for a sensitive sampling method. Vapors of known concentrations were generated in Tedlar gas bags by syringe injection of known volumes of formalin of measured formaldehyde content. Chemisorption through reaction with 20% (w /w) PFBHA on Tenax TA solid sorbent (200 mg) in a Pyrex tube (7-cm long, 7-mm OD, and 5-mm ID) occurred during collection with a personal sampling pump operated at 10 or 50 mL/ min. The oxime derivative was desorbed quantitatively (>75%) with hexane and an aliquot injected for gas chromatographic analys is on a nonpolar capillary column with 63(Ni) electron capture detection. Formaldehyde at 8 ppm-hours relative to the TLV-TWA concentration can be successfully sampled with a recovery of 94 +/- 4%. Valeraldehyde and acrolein at their TLV-TWAs H 8 hours showed no significant differences (P<0.05) between the recoveries at different relative humidities (1 and 90%) and sampling temperatures (1, 25, and 401C). The critical time for desorption was 30 minutes with occasional shaking or 2 minutes for vigorous manual shaking. The desorption efficiency for valeraldehyde is 88 +/- 2%, and the desorption efficiency for acrolein is 100 +/- 3%.
Airborne-particles; Air-monitoring; Air-quality-measurement; Air-sampling; Air-sampling-equipment; Air-sampling-techniques; Carcinogens; Exposure-assessment; Laboratory-testing; Mathematical-models; Quantitative-analysis; Sampling-methods; Standards; Vapor-detectors
Research Tools and Approaches: Exposure Assessment Methods
American Industrial Hygiene Conference and Exposition, May 9-15, 1998, Atlanta, Georgia
University of California Los Angeles, Los Angeles, CA