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Occupational lower airway disease in relation to World Trade Center inhalation exposure.

Authors
de la Hoz-RE
Source
Curr Opin Allergy Clin Immunol 2011 Apr; 11(2):97-102
NIOSHTIC No.
20039116
Abstract
PURPOSE OF REVIEW: To summarize the knowledge about the occupational lower airway diseases that seem related to exposures at the World Trade Center disaster site. RECENT FINDINGS: Those diseases have been characterized as irritant-induced asthma, chronic nonspecific bronchitis, chronic bronchiolitis/small airway disease, and aggravated preexistent chronic obstructive lung disease (most frequently chronic obstructive pulmonary disease, but also asthma), with the expected overlapping features among them. One remarkable characteristic of the irritant-induced asthma observed among these workers was the slow onset of symptoms and long delay in clinical diagnoses. SUMMARY: Longitudinal studies suggest that both the incidence and the associated functional decline of these predominantly obstructive lung diseases stabilized several years ago, but longer follow-up is clearly necessary.
Keywords
Rescue-workers; Emergency-responders; Respiratory-system-disorders; Pulmonary-system-disorders; Lung-disorders; Lung-function; Airway-obstruction; Bronchial-asthma; Chronic-inflammation; Disease-incidence; Lung-irritants; Epidemiology; Surveillance-programs; Medical-monitoring; Clinical-diagnosis; Medical-screening; Medical-services; Author Keywords: airway diseases; asthma; bronchial hyperreactivity; bronchiolitis; chronic obstructive pulmonary disease; inhalation injury; irritants; lung diseases; occupational diseases; toxic inhalation
Contact
Rafael E. de la Hoz, MD, MPH, WTC Monitoring and Treatment Program, Mount Sinai School of Medicine, Box 1059, One Gustave L. Levy Place, New York, NY 10029, USA
CODEN
COACCS
Publication Date
20110401
Document Type
Journal Article
Email Address
Rafael.delaHoz@mssm.edu
Funding Type
Cooperative Agreement
Fiscal Year
2011
NTIS Accession No.
NTIS Price
Identifying No.
Cooperative-Agreement-Number-U10-OH-008225; Cooperative-Agreement-Number-U10-OH-008232
Issue of Publication
2
ISSN
1528-4050
Source Name
Current Opinion in Allergy and Clinical Immunology
State
NY
Performing Organization
Mount Sinai School of Medicine of New York University
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