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Results of spirometry among individuals in a silicosis registry.

Authors
Rosenman-KD; Reilly-MJ; Gardiner-J
Source
J Occup Environ Med 2010 Dec; 52(12):1173-1178
NIOSHTIC No.
20038147
Abstract
Objective: To determine whether individuals with simple silicosis have obstructive and restrictive decrements. Methods: The prevalence of spirometric abnormalities by radiograph profusion, smoking, duration, and latency from first silica exposure was evaluated among confirmed silicotics. Results: Among 526 silicotics, 17.3% who had never smoked and 26.5% of smokers had obstruction, 30.1% and 28.1% had restriction, and 22.4% and 25.7% had a mixed obstructive and restrictive pattern. Individuals with category 3 profusion or progressive massive fibrosis were more likely to have abnormalities. Conclusion: Both obstructive and restrictive patterns were observed regardless of smoking status with a low profusion category of simple silicosis. There was an increased prevalence of restrictive changes with increased profusion. After controlling for age, smoking, and duration of exposure to silica, there was a statistically significant increased risk of obstructive and mixed changes with progressive massive fibrosis.
Keywords
Lung-disease; Lung-fibrosis; Silicosis; Respiratory-function-tests; Respiratory-irritants; Respiratory-system-disorders; Smoking; Pulmonary-disorders; Pulmonary-function-tests; Pulmonary-system-disorders; Spirometry; Epidemiology; Statistical-analysis; Demographic-characteristics
Contact
Kenneth D. Rosenman, MD, Professor of Medicine, Michigan State University, 117 West Fee, East Lansing, MI 48824
CODEN
JOEMFM
CAS No.
14808-60-7
Publication Date
20101201
Document Type
Journal Article
Email Address
Rosenman@msu.edu
Funding Type
Cooperative Agreement
Fiscal Year
2011
NTIS Accession No.
NTIS Price
Identifying No.
Cooperative-Agreement-Number-U60-OH-008466
Issue of Publication
12
ISSN
1076-2752
Source Name
Journal of Occupational and Environmental Medicine
State
MI
Performing Organization
Michigan State University
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