Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

NIOSHTIC-2 Publications Search

Search Results

Prevalence of norovirus among visitors from the United States to Mexico and Guatemala who experience traveler's diarrhea.

Authors
Chapin-AR; Carpenter-CM; Dudley-WC; Gibson-LC; Pratdesaba-R; Torres-O; Sanchez-D; Belkind-Gerson-J; Nyquist-I; Kärnell-A; Gustafsson-B; Halpern-JL; Bourgeois-AL; Schwab-KJ
Source
J Clin Microbiol 2005 Mar; 43(3):1112-1117
NIOSHTIC No.
20037350
Abstract
Traveler's diarrhea (TD) is the most common infectious illness acquired by visitors to developing nations. The purpose of this study was to utilize molecular diagnostic techniques to determine the prevalence of norovirus (NoV) in TD occurring among visitors from the United States to Guatemala and Mexico. Stool samples (n = 54) were collected from 34 TD cases and analyzed for NoV by reverse transcription-PCR and oligoprobe confirmation. The overall prevalence of NoV was 65%. Interestingly, all NoV-positive stool samples were identified as genogroup I NoVs, and time spent at travel destinations was found to be an important factor in determining the frequency of infection (P = 0.003). Eleven NoV-positive stool samples also tested positive for enterotoxigenic Escherichia coli, indicating that dual infections with this leading bacterial cause of TD were very common. Results of this study suggest that NoV infection is a frequent occurrence among travelers to Mexico and Guatemala who experience episodes of TD. In addition, the simple molecular detection method utilized here will serve to facilitate more in-depth epidemiological studies of this emergent viral pathogen in travelers and other at-risk populations.
Keywords
Bacteria; Bacterial-disease; Bacterial-infections; Diagnostic-tests; Diagnostic-techniques; Gastrointestinal-system; Gastrointestinal-system-disorders; Infectious-diseases
Contact
Kellogg J. Schwab, Johns Hopkins University Bloomberg School of Public Health, 615 N. Wolfe St., Room E6620, Baltimore, MD 21205
CODEN
JCMIDW
Publication Date
20050301
Document Type
Journal Article
Email Address
kschwab@jhsph.edu
Funding Type
Grant
Fiscal Year
2005
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-T42-OH-008428
Issue of Publication
3
ISSN
0095-1137
Source Name
Journal of Clinical Microbiology
State
MD
Performing Organization
Johns Hopkins University
TOP